DCTN2 and KIFC3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DCTN2	KIFC3
Gene Name		dynactin 2 (p50)	kinesin family member C3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Cytoplasm Centrosome Cytosol Dynactin Complex Microtubule Membrane Dynein Complex Growth Cone Vesicle Extracellular Vesicular Exosome	Golgi Apparatus Centrosome Kinesin Complex Microtubule Zonula Adherens Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome
	Molecular Function	Motor Activity Protein Binding Spectrin Binding	Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Spindle Organization Mitotic Nuclear Division Metabolic Process Cell Proliferation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Melanosome Transport	Microtubule-based Movement Golgi Organization Visual Perception Metabolic Process Zonula Adherens Maintenance Epithelial Cell-cell Adhesion
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition Anchoring of the basal body to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: BICD1 BICD2 BLOC1S6 CALM1 CCDC172 DISC1 EGFR GADD45A GNAO1 GOLM1 GRB2 GSK3B HAUS1 HGS KIFC3 KPNA2 MAPK6 MARCKSL1 PAFAH1B1 RPGR ZW10	91 interactors: ABI2 AES ANXA13 APP ARNT2 ATF2 BCL6 C1orf109 CBX8 CCDC102B CCDC136 CCDC28A CCDC33 CCDC67 CDK18 CDR2 CEP170P1 CEP55 CEP57L1 CLIP4 CREB5 CYTH4 DCTN2 DCX DTNBP1 ESRRG FAM124A FANCL FCHSD2 GMCL1 GOLGA2 GORASP2 HAUS1 HSBP1 ICA1L ITGB3BP KANSL1 KDM1A KRT15 KRT19 KRT31 KRT40 KRT5 KRT6A KRT6B KRT6C LENG1 LIN37 LZTS2 MCM7 MED4 MFAP1 MID2 MOS NDEL1 NECAB2 NEDD4 NEDD4L NEFL NUP62 PHC2 PRKAA2 PSMB1 RAD51D RSPH14 SCEL SIAH1 SMARCE1 SNAP29 SOX30 SOX5 SPERT SVIL SYCE1 TCEANC TNIP1 TPM3 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSR2 USP2 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF572 ZNF655
Entrez ID		10540	3801
HPRD ID		09568	05171
Ensembl ID		ENSG00000175203	ENSG00000140859
Uniprot IDs		Q13561	B7Z484 B7Z896 F5H4I9 Q9BVG8
PDB IDs			2H58
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Microtubule Cytoskeleton Organization Cellular Localization Microtubule-based Transport Protein Localization Cytoskeleton-dependent Intracellular Transport Movement Of Cell Or Subcellular Component Microtubule-based Movement Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Protein Localization Organelle Organization Establishment Of Localization In Cell Intracellular Transport Minus-end-directed Organelle Transport Along Microtubule Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Development Cerebral Cortex Development Negative Regulation Of ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization Organelle Transport Along Microtubule Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Generation Of Neurons Neuron Differentiation Cytoskeleton Organization Pallium Development Forebrain Development Cell Projection Organization Neurotrophin TRK Receptor Signaling Pathway Brain Development Cellular Response To Mechanical Stimulus Neurogenesis Neurotrophin Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Head Development Neuron Projection Development Nervous System Development Regulation Of ERBB Signaling Pathway Microtubule Anchoring At Microtubule Organizing Center Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Protein Localization To Organelle Cerebral Cortex Cell Migration Fc Receptor Signaling Pathway Cell Cycle Telencephalon Cell Migration Telencephalon Development	Cell Cycle Organelle Organization Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Gene Expression Regulation Of RNA Metabolic Process Mitotic Cell Cycle RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Gene Expression Cytoskeleton Organization Mitotic Cell Cycle Process RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Developmental Process Axon Cargo Transport Microtubule-based Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Macromolecule Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Protein Binding Regulation Of Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Protein K63-linked Ubiquitination Retrograde Axon Cargo Transport Protein Polyubiquitination Anatomical Structure Development Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Chromosome Organization Protein Monoubiquitination Cellular Nitrogen Compound Metabolic Process Reproduction Heterocycle Metabolic Process Microtubule Cytoskeleton Organization Cellular Aromatic Compound Metabolic Process
Tagcloud ?			18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kinesin kinesins mll1
Tagcloud (Difference) ?			18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kinesin kinesins mll1
Tagcloud (Intersection) ?