CLGN and ADAM2

Number of citations of the paper that reports this interaction (PMID 11784061)
17

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		CLGN	ADAM2
Gene Name		calmegin	ADAM metallopeptidase domain 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Calcium Ion Binding Protein Binding Involved In Protein Folding Unfolded Protein Binding	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Protein Folding Protein Complex Assembly Single Fertilization Binding Of Sperm To Zona Pellucida	Proteolysis Cell Adhesion Single Fertilization Binding Of Sperm To Zona Pellucida Fusion Of Sperm To Egg Plasma Membrane Visual Learning Adult Behavior Multicellular Organism Reproduction
Pathways			Interaction With The Zona Pellucida Fertilization
Drugs
Diseases
GWAS		Select biomarker traits ( 17903293)
Protein-Protein Interactions		3 interactors: ADAM2 GDE1 XK	2 interactors: CD9 CLGN
Entrez ID		1047	2515
HPRD ID		03513	03322
Ensembl ID		ENSG00000153132	ENSG00000104755
Uniprot IDs		O14967	B4DWY7 Q6P2G0 Q99965
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Magnesium Ion Homeostasis Regulation Of Axon Diameter Regulation Of Cell Projection Size Magnesium Ion Homeostasis Fusion Of Sperm To Egg Plasma Membrane Plasma Membrane Fusion Skeletal Muscle Fiber Development Glycerol Metabolic Process Myotube Cell Development	Single Fertilization Fertilization Response To Water Deprivation Sexual Reproduction Fusion Of Sperm To Egg Plasma Membrane Paranodal Junction Assembly Plasma Membrane Fusion Reproduction Myelin Assembly Single Organism Reproductive Process Reproductive Process Oligodendrocyte Development Binding Of Sperm To Zona Pellucida Sperm-egg Recognition Cell-cell Recognition Platelet Degranulation Oligodendrocyte Differentiation Cellular Component Assembly Glial Cell Development Cell-cell Junction Assembly Cell Recognition Membrane Fusion Myelination Axon Ensheathment Glial Cell Differentiation Platelet Activation Cell Junction Assembly Pathogenesis Cell-cell Junction Organization
Tagcloud ?		adam1a adam2 adam3 calmegin calnexin calr calr3 calreticulin calsperin canx chaperones client contraception contrasting cooperate fertility fertilization germ infertile infertility lectin nascent oviduct pave pellucida sperm unexplained uterus zona	adam1a adam3 calmegin calnexin calr calr3 calreticulin calsperin canx chaperones clgn client contraception contrasting cooperate fertility fertilization germ infertile infertility lectin nascent oviduct pave pellucida sperm unexplained uterus zona
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		adam1a adam2 adam3 calmegin calnexin calr calr3 calreticulin calsperin canx chaperones clgn client contraception contrasting cooperate fertility fertilization germ infertile infertility lectin nascent oviduct pave pellucida sperm unexplained uterus zona