CACNG2 and INADL

Number of citations of the paper that reports this interaction (PMID 16637659)
18

Data Source:
HPRD (in vitro)

		CACNG2	INADL
Gene Name		calcium channel, voltage-dependent, gamma subunit 2	InaD-like (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Endocytic Vesicle Membrane Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex	Plasma Membrane Tight Junction Apical Plasma Membrane Protein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Calcium Channel Activity Protein Binding Ionotropic Glutamate Receptor Binding	Protein Binding
	Biological Process	Transport Synaptic Transmission Neuromuscular Junction Development Transmission Of Nerve Impulse Membrane Depolarization Membrane Hyperpolarization Calcium Ion Transmembrane Transport Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity	Cell Junction Assembly Intracellular Signal Transduction Cell-cell Junction Organization Tight Junction Assembly
Pathways		Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses	Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		10 interactors: APP DLG1 DLG2 DLG3 DLG4 GRIA1 GRIA4 INADL PRKACA SRPK2	28 interactors: ASIC3 BAI1 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3
Entrez ID		10369	10207
HPRD ID		04220	04434
Ensembl ID			ENSG00000132849
Uniprot IDs		Q9Y698	Q8NI35
PDB IDs			1VF6 2D92 2DAZ 2DB5 2DLU 2DM8 2DMZ 2EHR
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Protein Localization To Synapse Synaptic Transmission Receptor Clustering Nucleotide Phosphorylation Cell-cell Signaling Establishment Or Maintenance Of Apical/basal Cell Polarity Signaling Ionotropic Glutamate Receptor Signaling Pathway Cell Communication Phosphorylation Glutamate Receptor Signaling Pathway Chemotaxis Signal Transduction Protein Localization To Membrane Membrane Organization Axon Guidance Cell-cell Junction Assembly Response To Stimulus Phosphate-containing Compound Metabolic Process Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cellular Component Assembly Axonogenesis Cortical Actin Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Nucleotide Metabolic Process Axon Development Cortical Cytoskeleton Organization Cell Junction Assembly Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Stimulus Cell-cell Junction Organization Locomotion Neuron Projection Morphogenesis Nucleobase-containing Small Molecule Metabolic Process Nervous System Development Small Molecule Metabolic Process Synaptic Transmission, Glutamatergic Regulation Of Catalytic Activity Cell Morphogenesis Involved In Differentiation Learning Or Memory Anatomical Structure Morphogenesis Regulation Of Phosphorus Metabolic Process Tight Junction Assembly Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Cycle Cognition Negative Regulation Of Catalytic Activity Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis	Synaptic Transmission Cell-cell Signaling Membrane Depolarization Regulation Of Membrane Potential Neurological System Process Cation Transmembrane Transport Ion Transmembrane Transport Neuron-neuron Synaptic Transmission Regulation Of Ion Transmembrane Transport Metal Ion Transport Ion Transport Cation Transport Signaling Cell Communication Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Transmembrane Transport Regulation Of Ion Transport Neuromuscular Process Regulation Of Neurological System Process Glutamate Receptor Signaling Pathway Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Potassium Ion Import Sensory Perception Of Pain Regulation Of Sensory Perception Of Pain Cell-cell Junction Organization Startle Response Monovalent Inorganic Cation Transport Directional Locomotion Membrane Depolarization During Action Potential Membrane Hyperpolarization Single-organism Behavior Gephyrin Clustering Transport Tight Junction Assembly Nervous System Development Regulation Of Resting Membrane Potential Postsynaptic Membrane Assembly Transmission Of Nerve Impulse Behavior Potassium Ion Transmembrane Transport Protein Localization To Membrane Glial Cell Differentiation Postsynaptic Density Protein 95 Clustering Neurogenesis Membrane Depolarization During Cardiac Muscle Cell Action Potential Apical Junction Assembly Potassium Ion Transport Response To Mechanical Stimulus
Tagcloud ?		ampa bioinformatics electrophysiological glutamatergic hypomorphic inbred integrative intimately list mapped narrow neuropathic pain1 physiology pinpoint precipitating predisposing predisposition progeny psychosocial qtl rist rpt segregation specifics stargazer stargazin trait ultimately	10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Difference) ?		ampa bioinformatics electrophysiological glutamatergic hypomorphic inbred integrative intimately list mapped narrow neuropathic pain1 physiology pinpoint precipitating predisposing predisposition progeny psychosocial qtl rist rpt segregation specifics stargazer stargazin trait ultimately	10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Intersection) ?