CDKN2D and C1orf94

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CDKN2D	C1orf94
Gene Name		cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	chromosome 1 open reading frame 94
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding	Protein Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Synthesis Involved In DNA Repair Cell Cycle Arrest Sensory Perception Of Sound Negative Regulation Of Cell Proliferation Response To UV Negative Regulation Of Cell Growth Response To Retinoic Acid Response To Vitamin D Negative Regulation Of Phosphorylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Autophagic Cell Death Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		Cyclin D associated events in G1 Oxidative Stress Induced Senescence G1 Phase Cellular Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		11 interactors: APP BRCA1 C1orf94 CDK4 CDK6 HSD17B14 IKZF3 INCA1 NR4A1 NR4A2 TBC1D17	60 interactors: ACTN3 AES AKAP9 ATRIP ATXN1 BANP BOLA1 BOLL BYSL C1orf109 C6orf165 CARD9 CCHCR1 CCNJL CDKN2D DAB1 DAZAP2 DGCR6 DOK6 DTX2 FAM168A FAM46D GCC1 GORASP2 GRB2 GSE1 HNRNPF HOXA1 IPO11 KLHL32 LMO2 MAGED1 MAPK1IP1L MAPK9 MEIS2 MVP NFKBID NGB OAZ3 OIP5 PITX1 PLEKHB2 PRKAG1 PRR20A R3HDM2 RAD51D RBFOX1 RBFOX2 RBM47 RBPMS ROR2 SMAP2 TBX6 TNPO2 TXNDC9 UBQLN4 USO1 VENTX VPS37C YES1
Entrez ID		1032	84970
HPRD ID		02957	11310
Ensembl ID		ENSG00000129355	ENSG00000142698
Uniprot IDs		P55273	Q6P1W5
PDB IDs		1BD8 1BI8
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Regulation Of Cell Death Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Response To Steroid Hormone Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation Positive Regulation Of Cell Cycle Process Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cell Cycle Regulation Of Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Cycle Phase Transition Response To Lipid Response To Organic Cyclic Compound Negative Regulation Of Protein Metabolic Process Positive Regulation Of Fibroblast Proliferation Response To Hormone Positive Regulation Of Histone H4-K20 Methylation Cell Dedifferentiation Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription From RNA Polymerase II Promoter Death Regulation Of Cellular Protein Metabolic Process Forebrain Development Response To Abiotic Stimulus Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Arrest Steroid Hormone Mediated Signaling Pathway Habenula Development Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation General Adaptation Syndrome Regulation Of Cell Cycle Process Adult Locomotory Behavior Regulation Of Gene Expression Anatomical Structure Development Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Metabolic Process	Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Phosphorylation Cell Cycle Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Developmental Process Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Arrangement Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Splicing Cell Migration In Hindbrain Regulation Of RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Response To Radiation Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cytoplasmic Transport Neuromuscular Process RNA Metabolic Process Positive Regulation Of Protein Metabolic Process Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Abducens Nerve Formation Optokinetic Behavior Regulation Of Erythrocyte Differentiation Response To Organic Substance Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Immune System Process Regulation Of Cellular Process Organ Development System Development Cell Differentiation Nucleobase-containing Compound Metabolic Process Regulation Of Kinase Activity Response To Light Stimulus Cellular Nitrogen Compound Metabolic Process Facial Nucleus Development Cerebellum Structural Organization Putrescine Transport Golgi Vesicle Docking
Tagcloud ?		arrests cdk4 characterization cloning conserved enforced evolution evolutionary fibroblasts functionally g1 identity indeed inhibiting ink4 ink4d lnk4d maternally mouse neurulation p19ink4d regulator substitute transcripts traverse vertebrate xenopus xenopuslaevis xl
Tagcloud (Difference) ?		arrests cdk4 characterization cloning conserved enforced evolution evolutionary fibroblasts functionally g1 identity indeed inhibiting ink4 ink4d lnk4d maternally mouse neurulation p19ink4d regulator substitute transcripts traverse vertebrate xenopus xenopuslaevis xl
Tagcloud (Intersection) ?