TRIM13 and GMCL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM13	GMCL1
Gene Name		tripartite motif containing 13	germ cell-less, spermatogenesis associated 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Endoplasmic Reticulum	Nuclear Envelope Nuclear Matrix
	Molecular Function	Ubiquitin-protein Transferase Activity Signal Transducer Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Signal Transduction Anatomical Structure Morphogenesis Response To Gamma Radiation Positive Regulation Of Cell Death Positive Regulation Of Macroautophagy ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Negative Regulation Of Viral Release From Host Cell	Regulation Of Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Cell Differentiation
Pathways
Drugs		Etorphine Diprenorphine Dihydromorphine
Diseases
GWAS		Height ( 23563607)
Protein-Protein Interactions		4 interactors: ARHGDIA GMCL1 ROBO2 UBE2D2	61 interactors: APLF APOL6 BYSL C21orf2 C5orf60 CCDC25 CHIC2 CIB3 CLK2 CUL3 EMD FAM167A FAM63A FKBP1B FOSL2 FOXR1 FRMD6 GAGE1 GAGE12B GAGE12I GAGE2E GAGE5 GLRX3 GMCL1P1 GRAMD1A HYKK IL17F KAT5 KIFC3 KPNA2 MID1 MID2 MORF4L1 MPPE1 MTRR NEBL NUMA1 PARD6B PARP16 PAX4 PBXIP1 PTPN7 QRICH1 RAD54B SHQ1 SLC15A3 SNX20 STK3 SUMO1 SUMO1P1 SYT17 TCEB3 TMPO TRIM13 TRIM38 TRIM54 TSG101 TSSC4 XAGE2 XAGE3 ZNF250
Entrez ID		10206	64395
HPRD ID		10414	13587
Ensembl ID		ENSG00000204977
Uniprot IDs		O60858	Q53SE7 Q96IK5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Axonogenesis Regulation Of Axonogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Negative Chemotaxis Apoptotic Process Involved In Luteolysis Positive Regulation Of Neuron Projection Development Regulation Of Negative Chemotaxis Negative Regulation Of Locomotion Luteolysis Axon Midline Choice Point Recognition Positive Regulation Of Cell Projection Organization Axon Choice Point Recognition Positive Regulation Of Neuron Differentiation Olfactory Bulb Interneuron Development Regulation Of Neuron Projection Development Positive Regulation Of Neurogenesis Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Olfactory Bulb Interneuron Differentiation Positive Regulation Of Cell Development Negative Regulation Of Synapse Assembly Regulation Of Neuron Differentiation Retinal Ganglion Cell Axon Guidance Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Chemotaxis Apoptotic Process Involved In Development Regulation Of Locomotion Regulation Of Neurogenesis Forebrain Neuron Development Neuron Recognition Protein K48-linked Ubiquitination Multicellular Organismal Reproductive Process Olfactory Bulb Development Multicellular Organism Reproduction Semaphorin-plexin Signaling Pathway Regulation Of Cell Development Positive Regulation Of Cell Differentiation Olfactory Lobe Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Rho Protein Signal Transduction Regulation Of Synapse Assembly Forebrain Neuron Differentiation TRIF-dependent Toll-like Receptor Signaling Pathway Cell Differentiation Negative Regulation Of Axonogenesis Reproduction MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Forebrain Generation Of Neurons	Protein Localization To Microtubule Double-strand Break Repair Regulation Of Viral Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Transcription Negative Regulation Of Viral Release From Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Axon Regeneration Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Transcription Protein Localization To Cytoskeleton Regulation Of Viral Release From Host Cell DNA Metabolic Process Cellular Protein Modification Process DNA Repair Trophectodermal Cell Differentiation Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Proteasomal Protein Catabolic Process Nucleus Organization Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Cellular Localization Negative Regulation Of Microtubule Depolymerization Cardiac Muscle Thin Filament Assembly Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Ubiquitin-dependent Protein Catabolic Process Blastocyst Formation Response To Ionizing Radiation Modification-dependent Protein Catabolic Process Cellular Response To Interferon-gamma
Tagcloud ?		anchored autophagy clonogenic dysregulation e3 endoplasmic essential hence ikk interacts kappab ligase modification modulates nemo neurodegenerative nf opposite regulator represses repression resident reticulum ring steps stimuli translational turnover ubiquitination	asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1
Tagcloud (Difference) ?		anchored autophagy clonogenic dysregulation e3 endoplasmic essential hence ikk interacts kappab ligase modification modulates nemo neurodegenerative nf opposite regulator represses repression resident reticulum ring steps stimuli translational turnover ubiquitination	asm atm bouquet compensate conjugating dmc1 doubling dsbs gadd45a haploid hop2 hr6b insignificant joining ku80 m1jcs mei1 meiosis mlh1 pairing preleptotene prophase segregates spermatocytes spermatogenesis spermiogenesis spo11 terf1 tnp1
Tagcloud (Intersection) ?