CDK4 and CDKN2B

  • Number of citations of the paper that reports this interaction (PMID 9163429)
  • 81
  • Data Source:
  • HPRD (in vitro, in vivo)

CDK4

CDKN2B

Gene Name cyclin-dependent kinase 4 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Celiac disease and Rheumatoid arthritis ( 21383967)
Protein-Protein Interactions 90 interactors: ANKRD12 ANXA7 APLP1 APP ARID4A ATP5B BAG6 BCL11A BIRC5 BMPR1B BRCA1 CAMK1 CAPNS1 CCND1 CCND2 CCND3 CDC37 CDC45 CDC6 CDC7 CDKN1A CDKN1B CDKN1C CDKN2A CDKN2B CDKN2C CDKN2D CEBPA CIB1 CNOT7 DAZAP2 DDAH2 DUSP9 FOXM1 GLI1 H1F0 HIST1H1A HIST1H1D HMGXB3 HOOK1 IFI27 IL15RA LUC7L2 MAPRE2 MARCKS MCM2 MYC MYOD1 MZF1 NCOA2 NOL12 ORC3 OTX2 PGD PKM POLD1 PPP2R1B PRKAR1A PSMD10 PTMA QARS RB1 RBL1 RBL2 RFC1 RFC4 RPL34 SENP3 SERTAD1 SETDB1 SHOX2 SKP1 SLBP SMAD2 SMAD3 SNCA TGFBR1 TK1 TRMT2A TSPYL2 UBTF UHRF2 VTA1 WDR33 ZBTB16 ZNF101 ZNF219 ZNF335 ZNF655 ZSCAN1 15 interactors: APP ARPC3 CCDC33 CCDC90B CDK4 CDK6 CDK8 IKBKAP ISL1 KIAA1377 MAGEA11 NIF3L1 TGFB1I1 TRAF1 ZBTB17
Entrez ID 1019 1030
HPRD ID 00447 02696
Ensembl ID ENSG00000135446 ENSG00000147883
Uniprot IDs P11802 Q6LC83 K7PPU3 P42772
PDB IDs 1LD2 2W96 2W99 2W9F 2W9Z 3G33
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aberrantly  acetylglucosaminyltransferase  antigens  bage  ctl  ecto  fig  fm3  fm57  gage  gp100  immunogenic  immunogenicity  in4  maa  mage  mart  melan  melanocyte  melanomas  p15  pbl  permitted  pointing  prame  ref  tab  trp  tyrosinase  uncloned 
a134c  abp  allelic  ankyrin  balb  cdk6  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p15  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Difference) ?
aberrantly  acetylglucosaminyltransferase  antigens  bage  ctl  ecto  fig  fm3  fm57  gage  gp100  immunogenic  immunogenicity  in4  maa  mage  mart  melan  melanocyte  melanomas  pbl  permitted  pointing  prame  ref  tab  trp  tyrosinase  uncloned 
a134c  abp  allelic  ankyrin  balb  cdk6  cdnas  chr  congenic  d2  dba  g232a  ifna  inbred  inefficient  ink4c  le  multigenic  mus  p16  p18  pctr1  plasmacytoma  pristane  spretus  typed 
Tagcloud (Intersection) ?
p15