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TOM1L1 and FAM208A
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
TOM1L1
FAM208A
Gene Name
target of myb1 (chicken)-like 1
family with sequence similarity 208, member A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Lysosome
Endosome
Golgi Stack
Cytosol
Endosome Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Clathrin Binding
Protein Kinase Activator Activity
Ubiquitin Binding
Poly(A) RNA Binding
Biological Process
Intracellular Protein Transport
Signal Transduction
Positive Regulation Of Protein Autophosphorylation
Activation Of Protein Kinase Activity
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Negative Regulation Of Mitotic Nuclear Division
Regulation Of DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
27 interactors:
AMFR
CCDC47
CELF1
COPS7A
CWF19L1
FAM208A
FYN
GLUD2
GRB2
GSN
HGS
HNRNPH1
MAP3K3
NDC80
NOMO1
PDPN
PELP1
PHYH
PIK3R1
PWP2
RAB18
TOLLIP
TSG101
TUBA1B
UBXN4
VAV2
VCP
3 interactors:
AP2M1
TBC1D4
TOM1L1
Entrez ID
10040
23272
HPRD ID
05266
10183
Ensembl ID
ENSG00000141198
ENSG00000163946
Uniprot IDs
B7Z9E2
I3L4I4
O75674
Q9UK61
PDB IDs
3RRU
Enriched GO Terms of Interacting Partners
?
Phosphatidylinositol-mediated Signaling
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Response To Endoplasmic Reticulum Stress
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Platelet Activation
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Neurotrophin TRK Receptor Signaling Pathway
T Cell Costimulation
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Response To Organic Substance
Phagocytosis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of RNA Splicing
Fc Receptor Signaling Pathway
ER-nucleus Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Activation
Wound Healing
Response To Unfolded Protein
Response To Stress
Intracellular Signal Transduction
Cellular Response To Organic Substance
Cellular Component Assembly
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Vesicle-mediated Transport
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Activation
Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Complex Assembly
Response To Wounding
ER-associated Ubiquitin-dependent Protein Catabolic Process
Blood Coagulation
Hemostasis
Cellular Response To Stimulus
Cellular Response To Fibroblast Growth Factor Stimulus
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Response To Fibroblast Growth Factor
Positive Regulation Of Lys63-specific Deubiquitinase Activity
Positive Regulation Of Protein K63-linked Deubiquitination
NFAT Protein Import Into Nucleus
Regulation Of Phosphatidylinositol 3-kinase Activity
Negative Regulation Of ERBB Signaling Pathway
Signal Transduction
Immune Response-regulating Signaling Pathway
Positive Regulation Of T Cell Activation
Regulation Of Cellular Component Organization
Negative Regulation Of Vesicle Fusion
Tagcloud
?
adaptor
behave
bridged
clathrin
cytosolic
defective
egf
egfr
elusive
endocytic
endocytosis
endosome
engage
exogenous
grb2
incapable
knocked
machinery
onto
participate
redistributes
rescue
rnai
shc
stimulates
tail
transient
triggers
tyr
Tagcloud (Difference)
?
adaptor
behave
bridged
clathrin
cytosolic
defective
egf
egfr
elusive
endocytic
endocytosis
endosome
engage
exogenous
grb2
incapable
knocked
machinery
onto
participate
redistributes
rescue
rnai
shc
stimulates
tail
transient
triggers
tyr
Tagcloud (Intersection)
?