UBE3C

Gene Name		ubiquitin protein ligase E3C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteasome Complex Intracellular Nucleus Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ligase Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Quantitative traits ( 19197348) Response to citalopram treatment ( 19846067)
Protein-protein Interactions		10 interactors: APP CAND2 GOLGA2 MTA2 PSMC5 PSMD2 TLK1 UBC UBE2D1 UBE2L3
Entrez ID		9690
HPRD ID		15604
Ensembl ID		ENSG00000009335
Uniprot IDs		Q15386
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Ubiquitination Protein Polyubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Cellular Protein Modification Process Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Mitotic Cell Cycle Mitotic Cell Cycle Checkpoint Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Proteolysis Involved In Cellular Protein Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Positive Regulation Of Cell Cycle Process Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process Cell Cycle Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Cellular Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint
Tagcloud ?		aberrantly aforementioned aurkb bcrp bortezomib ccnb1 cd138 cdc2 cenp centrosome downregulate entity epc1 evidences g2 immunomodulatory incurable initiating lenalidomide mdr1 myeloma organs polycomb possess proteasome psma5 sp upregulated works