CD58

Gene Name		CD58 molecule
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Binding Protein Binding
	Biological Process	Cell Adhesion Blood Coagulation Single Organismal Cell-cell Adhesion Heterotypic Cell-cell Adhesion Leukocyte Migration Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Positive Regulation Of Interleukin-8 Secretion
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Multiple sclerosis ( 22190364 21244703 19525953 19525955 21833088)
Protein-protein Interactions		4 interactors: APP CD2 DNAJA1 HERPUD1
Entrez ID		965
HPRD ID		01081
Ensembl ID		ENSG00000116815
Uniprot IDs		P19256
PDB IDs		1CCZ 1CI5 1QA9
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Protein Kinase Activity Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Myeloid Dendritic Cell Activation Response To Unfolded Protein Negative Regulation Of Protein Metabolic Process Regulation Of Protein Binding Apoptotic Process Programmed Cell Death Synaptic Growth At Neuromuscular Junction Cell Death Death Regulation Of Protein Phosphorylation Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Response To Stress Collateral Sprouting In Absence Of Injury Membrane Raft Polarization Locomotion Positive Regulation Of Interferon-gamma Secretion Regulation Of Phosphorylation Regulation Of Binding Negative Regulation Of Endopeptidase Activity Collateral Sprouting Axon Midline Choice Point Recognition Membrane Raft Localization Negative Regulation Of Peptidase Activity Cellular Calcium Ion Homeostasis Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Myeloid Dendritic Cell Activation Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Calcium Ion Homeostasis Axon Choice Point Recognition Negative Regulation Of Proteolysis DNA Damage Response, Detection Of DNA Damage Negative Regulation Of Protein Processing Neuron Remodeling Positive Regulation Of Interleukin-8 Secretion Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Cellular Metal Ion Homeostasis Regulation Of Peptidase Activity Negative Regulation Of Intracellular Signal Transduction Blood Coagulation
Tagcloud ?		amixl atl bc blast burkitt cd54 cd80 cd86 cll cml costimulatory crisis dr granular hematological hla immuno lgl lymphoblastic lymphocytic lymphoma malignancies manipulating modality myeloblastic neoplastic ph1 philadelphia sharply