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CD8B
Gene Name
CD8b molecule
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Early Endosome Membrane
T Cell Receptor Complex
Molecular Function
Protein Binding
Coreceptor Activity
MHC Class I Protein Binding
Biological Process
Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Viral Process
T Cell Activation
Regulation Of Defense Response To Virus By Virus
Regulation Of Immune Response
Pathways
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
HIV Infection
Host Interactions of HIV factors
Nef Mediated CD8 Down-regulation
The role of Nef in HIV-1 replication and disease pathogenesis
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Adaptive Immune System
Drugs
Diseases
GWAS
Progressive supranuclear palsy (
21685912
)
Protein-protein Interactions
3 interactors:
CD3D
CD8A
ST3GAL4
Entrez ID
926
HPRD ID
01725
Ensembl ID
ENSG00000172116
Uniprot IDs
P10966
PDB IDs
Enriched GO Terms of Interacting Partners
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Cytotoxic T Cell Differentiation
T Cell Differentiation
Lymphocyte Differentiation
T Cell Aggregation
T Cell Activation
Lymphocyte Aggregation
Leukocyte Aggregation
Leukocyte Cell-cell Adhesion
Homotypic Cell-cell Adhesion
Leukocyte Differentiation
Lymphocyte Activation
Positive Thymic T Cell Selection
Leukocyte Activation
Single Organismal Cell-cell Adhesion
Hemopoiesis
Cell Activation
Immune System Development
Thymic T Cell Selection
Keratan Sulfate Biosynthetic Process
Positive T Cell Selection
Positive Regulation Of Calcium-mediated Signaling
Keratan Sulfate Metabolic Process
Regulation Of Immune Response
T Cell Mediated Immunity
T Cell Selection
Regulation Of Calcium-mediated Signaling
O-glycan Processing
Sialylation
Dolichol-linked Oligosaccharide Biosynthetic Process
Cell Adhesion
T Cell Differentiation In Thymus
Regulation Of Immune System Process
T Cell Costimulation
Protein O-linked Glycosylation
Glycosaminoglycan Biosynthetic Process
Protein N-linked Glycosylation Via Asparagine
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