STRADA

Gene Name		STE20-related kinase adaptor alpha
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Protein Export From Nucleus Cell Cycle Arrest Insulin Receptor Signaling Pathway Activation Of Protein Kinase Activity Intracellular Signal Transduction Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways		Insulin receptor signalling cascade IRS-mediated signalling Regulation of AMPK activity via LKB1 mTOR signalling IRS-related events mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R IRS-mediated signalling Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade PKB-mediated events PI3K Cascade Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CAB39 STK11 XPO1
Entrez ID		92335
HPRD ID		14332
Ensembl ID		ENSG00000266173
Uniprot IDs		Q7RTN6 Q86YC8
PDB IDs		1UPK 2WTK 3GNI
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Cycle Protein Heterooligomerization Cell Cycle Arrest Insulin Receptor Signaling Pathway TCR Signalosome Assembly Regulation Of Cellular Response To Growth Factor Stimulus Cell Cycle Cellular Response To Insulin Stimulus Ribosomal Small Subunit Export From Nucleus Negative Regulation Of Rubidium Ion Transport Negative Regulation Of Rubidium Ion Transmembrane Transporter Activity Activation Of Protein Kinase Activity Response To Insulin Cellular Response To Organic Substance Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Regulation Of Rubidium Ion Transport Anoikis Regulation Of Protein Metabolic Process Regulation Of Cellular Amino Acid Metabolic Process Cellular Response To UV-B Ribosomal Large Subunit Export From Nucleus Organelle Localization Protein Oligomerization Negative Regulation Of Cell Cycle Response To Peptide Hormone Ribosomal Subunit Export From Nucleus Positive Regulation Of Protein Kinase Activity Cellular Response To Organonitrogen Compound Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Thymic T Cell Selection Response To Peptide Response To Organic Substance Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Transferase Activity Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Hormone Stimulus Cellular Hypotonic Response Golgi Localization Positive Regulation Of Peptidyl-threonine Phosphorylation Response To UV-B Hypotonic Response Positive Regulation Of Gluconeogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
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