F2RL3

Gene Name		coagulation factor II (thrombin) receptor-like 3
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Thrombin Receptor Activity
	Biological Process	Signal Transduction Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Blood Coagulation Response To Wounding Platelet Activation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Platelet Dense Granule Organization Thrombin Receptor Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events Signaling by GPCR Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: F2 F2RL2
Entrez ID		9002
HPRD ID		04148
Ensembl ID
Uniprot IDs		Q96RI0
PDB IDs		2ZPK 3QDZ
Enriched GO Terms of Interacting Partners?		Platelet Activation Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Negative Regulation Of Fibrinolysis Cell Activation Response To Wounding Thrombin Receptor Signaling Pathway Peptidyl-glutamic Acid Carboxylation Regulation Of Fibrinolysis Blood Coagulation, Intrinsic Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Platelet Activation Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Collagen Metabolic Process Regulation Of Astrocyte Differentiation Fibrinolysis Regulation Of Platelet Activation Positive Regulation Of Blood Coagulation Negative Regulation Of Glial Cell Differentiation Regulation Of Collagen Metabolic Process Positive Regulation Of Calcium Ion Transport Into Cytosol Acute-phase Response Positive Regulation Of Coagulation Positive Regulation Of Wound Healing Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Wound Healing Acute Inflammatory Response Regulation Of Glial Cell Differentiation Regulation Of Calcium Ion Transport Into Cytosol Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Calcium Ion Transport Regulation Of Blood Coagulation Regulation Of Gliogenesis Positive Regulation Of Cell Growth Regulation Of Wound Healing Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Cell Shape Regulation Of Ion Homeostasis Protein Activation Cascade Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cytosolic Calcium Ion Homeostasis
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