CDKL1

Gene Name		cyclin-dependent kinase-like 1 (CDC2-related kinase)
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Protein Phosphorylation Heart Development Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193)
Protein-protein Interactions		2 interactors: SMURF1 TGFBR1
Entrez ID		8814
HPRD ID		10348
Ensembl ID
Uniprot IDs		J3KMW1 Q00532
PDB IDs		4AGU
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Cellular Response To Growth Factor Stimulus Response To Growth Factor Parathyroid Gland Development Endothelial Cell Activation Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of SMAD Protein Import Into Nucleus Enzyme Linked Receptor Protein Signaling Pathway Germ Cell Migration Protein Localization To Cell Surface Receptor Catabolic Process Pharyngeal System Development Response To Cholesterol Ectoderm Development Negative Regulation Of Chondrocyte Differentiation Negative Regulation Of Signal Transduction Cardiac Epithelial To Mesenchymal Transition Activin Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cartilage Development Positive Regulation Of Filopodium Assembly Protein Export From Nucleus Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Filopodium Assembly Peptidyl-threonine Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Artery Morphogenesis Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Thymus Development Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Collagen Fibril Organization Positive Regulation Of Endothelial Cell Proliferation Embryonic Cranial Skeleton Morphogenesis Artery Development Tissue Development Activation Of MAPKK Activity Regulation Of Chondrocyte Differentiation
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