IL1RL2

Gene Name		interleukin 1 receptor-like 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane
	Molecular Function	Interleukin-1 Receptor Activity Interleukin-1, Type I, Activating Receptor Activity
	Biological Process	Inflammatory Response Cellular Defense Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-6 Production Innate Immune Response Positive Regulation Of T Cell Differentiation Regulation Of Inflammatory Response Interleukin-1-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		1 interactors: IL18
Entrez ID		8808
HPRD ID		05150
Ensembl ID		ENSG00000115598
Uniprot IDs		A4FU63 Q9HB29
PDB IDs
Enriched GO Terms of Interacting Partners?		Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process Chemokine Biosynthetic Process Interleukin-13 Biosynthetic Process Interferon-gamma Biosynthetic Process Positive Regulation Of NK T Cell Proliferation Interleukin-2 Biosynthetic Process Positive Regulation Of Natural Killer Cell Proliferation Regulation Of Natural Killer Cell Proliferation Chemokine Metabolic Process Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Interleukin-2 Production Chemokine Production Type 2 Immune Response Positive Regulation Of Interleukin-17 Production Positive Regulation Of Alpha-beta T Cell Proliferation Sleep Interferon-gamma Production Positive Regulation Of NF-kappaB Import Into Nucleus Negative Regulation Of Myoblast Differentiation Positive Regulation Of Activated T Cell Proliferation Cytokine Biosynthetic Process Positive Regulation Of Natural Killer Cell Activation T-helper 1 Type Immune Response Positive Regulation Of Tissue Remodeling Cytokine Metabolic Process Regulation Of Activated T Cell Proliferation Positive Regulation Of Transcription Factor Import Into Nucleus Lipopolysaccharide-mediated Signaling Pathway Regulation Of NF-kappaB Import Into Nucleus Regulation Of Myoblast Differentiation Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Interferon-gamma Production Natural Killer Cell Activation Regulation Of Tissue Remodeling Positive Regulation Of T Cell Proliferation Regulation Of Interferon-gamma Production Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Inflammatory Response Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Cytokine Production Regulation Of T Cell Proliferation Regulation Of Muscle Cell Differentiation Cellular Response To Lipopolysaccharide Positive Regulation Of Intracellular Protein Transport Cellular Response To Molecule Of Bacterial Origin Regulation Of Protein Import Into Nucleus
Tagcloud ?		36gamma 36r alarmin atopic augments camp cathelicidin ccl20 cxcl1 cxcl10 dermatitis dermatoses exacerbations il1rap il36g il36gamma il36r il8 ip10 keratinocytes lesional ll37 mip3a nonlesional occasional pertussis psoriasis rosacea wounding