LHX3

Gene Name		LIM homeobox 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Placenta Development Transcription From RNA Polymerase II Promoter Motor Neuron Axon Guidance Organ Morphogenesis Spinal Cord Motor Neuron Cell Fate Specification Ventral Spinal Cord Interneuron Specification Medial Motor Column Neuron Differentiation Spinal Cord Association Neuron Differentiation Pituitary Gland Development Lung Development Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Inner Ear Development
Pathways
Drugs
Diseases
GWAS		Height ( 20189936) Thyroid hormone levels ( 23408906)
Protein-protein Interactions		8 interactors: CITED2 IFT172 ISL1 ISL2 LDB1 LHX1 LMX1A RLIM
Entrez ID		8022
HPRD ID		02783
Ensembl ID		ENSG00000107187
Uniprot IDs		F1T0D5 F1T0D7 F1T0D9 Q9UBR4
PDB IDs
Enriched GO Terms of Interacting Partners?		Central Nervous System Neuron Differentiation Ventral Spinal Cord Development Cell Differentiation In Spinal Cord Spinal Cord Development Axis Specification Central Nervous System Development Pattern Specification Process Visceral Motor Neuron Differentiation Neuron Differentiation Spinal Cord Motor Neuron Differentiation Anatomical Structure Morphogenesis Brain Development Generation Of Neurons Head Development Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Organ Development Axon Guidance Peripheral Nervous System Neuron Development Cerebellum Development Left/right Axis Specification Metencephalon Development Anatomical Structure Formation Involved In Morphogenesis Cell Morphogenesis Cell Differentiation Cerebellar Purkinje Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Spinal Cord Motor Neuron Cell Fate Specification Embryo Development Cell Projection Organization Cerebellar Purkinje Cell Layer Morphogenesis Axonogenesis Nervous System Development Transcription, DNA-templated Hindbrain Development Axon Development Left/right Pattern Formation Retinal Ganglion Cell Axon Guidance Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Organ Morphogenesis RNA Biosynthetic Process Negative Regulation Of Gene Expression Chemotaxis Negative Regulation Of Biosynthetic Process Negative Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Cerebellar Cortex Formation
Tagcloud ?		balanced binary circuit collaboration cord directing diversification enhancers excitatory expense fate gabaergic gata2 generating glutamatergic immature initiates interneuons interneuron interneurons lim lmo4 nli nucleates spinal v2 v2a v2b ventral