BHLHE41

Gene Name		basic helix-loop-helix family, member e41
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding MRF Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Circadian Rhythm Cell Proliferation Organ Morphogenesis Negative Regulation Of Myotube Differentiation Negative Regulation Of Transcription By Competitive Promoter Binding Cell Differentiation Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated
Pathways		BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: BHLHE40 MYOD1 SIRT1
Entrez ID		79365
HPRD ID		16204
Ensembl ID		ENSG00000123095
Uniprot IDs		B7Z8M6 Q8TAT1 Q9C0J9
PDB IDs
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Gene Expression Cellular Response To Oxygen Levels Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Peptidyl-lysine Acetylation Protein Acetylation Cellular Response To Starvation Response To Abiotic Stimulus Establishment Of Chromatin Silencing Negative Regulation Of Prostaglandin Biosynthetic Process Negative Regulation Of Cellular Response To Testosterone Stimulus Circadian Rhythm Cellular Response To Nutrient Levels Response To Starvation Myoblast Fate Determination Behavioral Response To Starvation Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Fiber Adaptation Cellular Response To Extracellular Stimulus Peptidyl-lysine Modification Maintenance Of Chromatin Silencing Negative Regulation Of Helicase Activity Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of Chromatin Silencing Muscle Organ Development Positive Regulation Of CAMP-dependent Protein Kinase Activity Positive Regulation Of Cellular Senescence Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Skeletal Muscle Tissue Regeneration Pyrimidine Dimer Repair By Nucleotide-excision Repair Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Skeletal Muscle Fiber Development Histone Modification Peptidyl-lysine Deacetylation Methylation-dependent Chromatin Silencing Negative Regulation Of CAMP-dependent Protein Kinase Activity Myoblast Fate Commitment Positive Regulation Of MHC Class II Biosynthetic Process Transcription, DNA-templated Response To Nutrient Levels Positive Regulation Of Cell Aging Triglyceride Mobilization Cellular Triglyceride Homeostasis Response To Radiation RNA Biosynthetic Process Skeletal Muscle Adaptation Negative Regulation Of Cellular Senescence Response To Extracellular Stimulus
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