VARS

Gene Name		valyl-tRNA synthetase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol
	Molecular Function	Aminoacyl-tRNA Editing Activity Valine-tRNA Ligase Activity ATP Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Valyl-tRNA Aminoacylation Regulation Of Translational Fidelity Gene Expression
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs		L-Valine
Diseases
GWAS
Protein-protein Interactions		4 interactors: CACNA1A CALCOCO2 EEF1D YWHAQ
Entrez ID		7407
HPRD ID		10362
Ensembl ID		ENSG00000204394
Uniprot IDs		P26640
PDB IDs
Enriched GO Terms of Interacting Partners?		Neural Nucleus Development Cerebellar Molecular Layer Development Vestibular Nucleus Development Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Gamma-aminobutyric Acid Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Negative Regulation Of Hormone Biosynthetic Process Pons Development Cerebellar Purkinje Cell Differentiation Cerebellar Purkinje Cell Layer Morphogenesis Reflex Behavioral Response To Pain Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Neuromuscular Synaptic Transmission Regulation Of Hormone Biosynthetic Process Cerebellar Cortex Formation Regulation Of Establishment Of Protein Localization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Neurotransmitter Metabolic Process Gamma-aminobutyric Acid Signaling Pathway Cell Differentiation In Hindbrain Calcium Ion Import Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Hormone Metabolic Process Cerebellar Purkinje Cell Layer Development Membrane Depolarization During Action Potential Brain Development Substantia Nigra Development Regulation Of Protein Localization Head Development Response To Pain Cerebellar Cortex Morphogenesis Synaptic Transmission, Glutamatergic Sulfur Amino Acid Metabolic Process Musculoskeletal Movement Membrane Organization Calcium Ion-dependent Exocytosis Spinal Cord Motor Neuron Differentiation Anion Homeostasis Regulation Of Signaling Adult Walking Behavior Cerebellum Morphogenesis Receptor Clustering Hindbrain Morphogenesis
Tagcloud ?		affymetrix aimps aminoacyl arsn arss atlas atp5c1 cars druggable dtgs fars gbm hsp90aa1 integrative interactors krt10 med12 multiforme nars pard3 pathologically ppis qars rxrb synthetases tcga thra versatility