TRPC6

Gene Name		transient receptor potential cation channel, subfamily C, member 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Slit Diaphragm
	Molecular Function	Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Cation Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Axon Guidance Aging Blood Coagulation Platelet Activation Positive Regulation Of Ion Transmembrane Transporter Activity Ion Transmembrane Transport Positive Regulation Of Calcium Ion Transport Transmembrane Transport Cellular Response To Hydrogen Peroxide Calcium Ion Transmembrane Transport Cellular Response To Hypoxia
Pathways		G alpha (q) signalling events Signaling by GPCR Axon guidance TRP channels Effects of PIP2 hydrolysis Platelet calcium homeostasis G alpha (q) signalling events GPCR downstream signaling Ion channel transport Platelet homeostasis Role of second messengers in netrin-1 signaling Gastrin-CREB signalling pathway via PKC and MAPK Elevation of cytosolic Ca2+ levels Stimuli-sensing channels Platelet activation, signaling and aggregation Netrin-1 signaling
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: FYN ITPR3 MX1 ORAI1 RNF24 SRC TRPC3 TRPC7 TRPM2
Entrez ID		7225
HPRD ID		04710
Ensembl ID		ENSG00000137672
Uniprot IDs		Q9Y210
PDB IDs
Enriched GO Terms of Interacting Partners?		Calcium Ion Transport Blood Coagulation Hemostasis Platelet Activation Calcium Ion Transmembrane Transport Regulation Of Body Fluid Levels Wound Healing Response To Wounding Metal Ion Transport Response To Stress Cation Transport Cell Activation Vascular Endothelial Growth Factor Receptor Signaling Pathway Ion Transport Manganese Ion Transmembrane Transport Cation Transmembrane Transport Axon Guidance Manganese Ion Transport Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Axonogenesis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Axon Development Cell Morphogenesis Involved In Neuron Differentiation Ion Transmembrane Transport Response To Hydroperoxide Chemotaxis Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neuron Projection Morphogenesis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cell Morphogenesis Involved In Differentiation Phagocytosis Peptidyl-tyrosine Autophosphorylation Fc Receptor Signaling Pathway Innate Immune Response Neuron Projection Development Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Projection Morphogenesis Transmembrane Transport Cell Part Morphogenesis Transport Response To External Stimulus Neuron Development
Tagcloud ?		blocker ca casr channels depending elicited eliminated exchanger expressions ip3 lymphocytes nicl2 nps plc rise sensing sepsis septic skf96365 sr stores tg thapsigargin transient trpc3 u73122 verapamil