TIAM1

Gene Name		T-cell lymphoma invasion and metastasis 1
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Gene Ontology Annotations	Cellular Component	Cytosol Cell-cell Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cell-cell Contact Zone
	Molecular Function	Receptor Signaling Protein Activity Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity Phospholipid Binding Rac Guanyl-nucleotide Exchange Factor Activity Ephrin Receptor Binding
	Biological Process	Cell-matrix Adhesion Small GTPase Mediated Signal Transduction Axon Guidance Cell Migration Rac Protein Signal Transduction Positive Regulation Of Rho GTPase Activity Positive Regulation Of Rac GTPase Activity Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Positive Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Apoptotic Signaling Pathway
Pathways		Signaling by GPCR Signalling by NGF Axon guidance Cell death signalling via NRAGE, NRIF and NADE p75 NTR receptor-mediated signalling Rho GTPase cycle EPHB-mediated forward signaling GPCR downstream signaling EPH-ephrin mediated repulsion of cells NRAGE signals death through JNK Signaling by Rho GTPases EPH-Ephrin signaling G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Renal sinus fat ( 22044751)
Protein-protein Interactions		25 interactors: ABCA1 ANK1 BTRC CAMK2G CD44 CSNK1A1 EFNB1 EPHA2 HRAS MAPK8IP1 MAPK8IP2 MYC NME1 PARD3 PPP1R9B PRKCA PRKCB PRKCD PRKCE PRKCG PRKCZ RAC1 SRC UBC YWHAG
Entrez ID		7074
HPRD ID		02820
Ensembl ID		ENSG00000156299
Uniprot IDs		Q13009
PDB IDs		2D8I 3KZD 3KZE 4GVC 4GVD 4K2O 4K2P
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphorus Metabolic Process Cellular Response To Organic Substance Signal Transduction Response To Growth Factor Regulation Of Phosphorylation Signaling Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Cell Communication Cellular Response To Growth Factor Stimulus Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Regulation Of MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Regulation Of Signaling Regulation Of Protein Metabolic Process Cell Surface Receptor Signaling Pathway Phosphorylation Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Catalytic Activity Blood Coagulation Wound Healing Hemostasis Cell Cycle Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Platelet Activation Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Response To Wounding Neurotrophin Signaling Pathway Apoptotic Process Phosphate-containing Compound Metabolic Process Programmed Cell Death Response To Stress Response To Stimulus Cell Death Regulation Of Body Fluid Levels Death Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Catalytic Activity Regulation Of Cell Death Defense Response
Tagcloud ?		biosynthesis boosting carefully causative defense es extend generating glycosylphosphatidylinositol live longevity mercaptoethanol mutagenized mutants nadph offers omission oxidase paraquat pigl platform pluripotency rffl select span stressors throughput transmit uncharacterized