SPR

Gene Name		sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Aldo-keto Reductase (NADP) Activity Sepiapterin Reductase Activity NADP Binding
	Biological Process	L-phenylalanine Metabolic Process Tetrahydrobiopterin Biosynthetic Process Nitric Oxide Biosynthetic Process Death Pteridine Metabolic Process Regulation Of Multicellular Organism Growth Norepinephrine Metabolic Process Dopamine Metabolic Process Serotonin Metabolic Process Small Molecule Metabolic Process Nitric Oxide Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Voluntary Musculoskeletal Movement Regulation Of Nitric-oxide Synthase Activity Oxidation-reduction Process
Pathways		Metabolism of nitric oxide eNOS activation and regulation Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs		Oxaloacetate Ion 2\'-Monophosphoadenosine 5\'-Diphosphoribose Biopterin N-Acetyl Serotonin
Diseases
GWAS
Protein-protein Interactions		2 interactors: CAMK2G YWHAQ
Entrez ID		6697
HPRD ID		01632
Ensembl ID		ENSG00000116096
Uniprot IDs		P35270
PDB IDs		1Z6Z 4HWK 4J7U
Enriched GO Terms of Interacting Partners?		Regulation Of Relaxation Of Cardiac Muscle Regulation Of Relaxation Of Muscle Regulation Of Skeletal Muscle Adaptation Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Response To Heat Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Substantia Nigra Development Insulin Secretion Protein Transport Establishment Of Protein Localization Neural Nucleus Development Positive Regulation Of Mitochondrion Organization Cellular Response To Heat Peptide Hormone Secretion Peptide Secretion Protein Localization Hormone Secretion Midbrain Development Establishment Of Localization In Cell Hormone Transport Regulation Of Mitochondrion Organization Peptide Transport
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