BOK

Gene Name		BCL2-related ovarian killer
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity BH Domain Binding
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Brain Development Cell Proliferation Male Gonad Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Oligodendrocyte Differentiation Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Execution Phase Of Apoptosis
Pathways
Drugs
Diseases
GWAS		Brain structure ( 20171287) Prostate cancer ( 23535732)
Protein-protein Interactions		3 interactors: BCL2A1 MCL1 NOA1
Entrez ID		666
HPRD ID		05657
Ensembl ID		ENSG00000176720
Uniprot IDs		Q9UMX3
PDB IDs
Enriched GO Terms of Interacting Partners?		Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Intrinsic Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Mitochondrion Organization Positive Regulation Of Oxidative Stress-induced Cell Death Negative Regulation Of Intracellular Signal Transduction Regulation Of Cellular Respiration Negative Regulation Of Anoikis Regulation Of Anoikis Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Response To DNA Damage Stimulus Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Negative Regulation Of Signal Transduction Regulation Of Cellular Response To Oxidative Stress Cell Fate Determination Negative Regulation Of Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Transmembrane Transport Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Neuron Apoptotic Process Apoptotic Mitochondrial Changes Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Neuron Death Mitochondrial Translation Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Apoptotic Process Cellular Response To Stress Regulation Of Intracellular Signal Transduction Regulation Of Response To DNA Damage Stimulus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Intracellular Signal Transduction Ribosome Biogenesis Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway
Tagcloud ?		acridine ameliorated arrested atf3 bak1 bax bromide bromodeoxyuridine cdk1 cullin cytoprotective defect diablo downregulated embryo embryos ethidium evaluating expressions morphologic mumol noxa nuclei orange pifithrin reproductive resveratrol smac toxin