SLC6A3

Gene Name		solute carrier family 6 (neurotransmitter transporter), member 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Axon Neuronal Cell Body
	Molecular Function	Protease Binding Receptor Binding Dopamine Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Protein Binding Drug Binding Monoamine Transmembrane Transporter Activity Protein Complex Binding Dopamine Binding Protein N-terminus Binding
	Biological Process	Neurotransmitter Transport Synaptic Transmission Aging Lactation Sensory Perception Of Smell Locomotory Behavior Response To Iron Ion Monoamine Transport Dopamine Transport Adenohypophysis Development Response To Nicotine Positive Regulation Of Multicellular Organism Growth Regulation Of Dopamine Metabolic Process Neurotransmitter Biosynthetic Process Response To Cocaine Dopamine Biosynthetic Process Dopamine Catabolic Process Response To Drug Response To Ethanol Response To CAMP Transmembrane Transport Prepulse Inhibition Ammonium Transmembrane Transport Cation Transmembrane Transport
Pathways		Na+/Cl- dependent neurotransmitter transporters Dopamine clearance from the synaptic cleft Neurotransmitter Clearance In The Synaptic Cleft Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC-mediated transmembrane transport Transmission across Chemical Synapses
Drugs		Amphetamine Phentermine Benzatropine Venlafaxine Methylphenidate Duloxetine Mazindol Procaine Trimipramine Modafinil Phenmetrazine Pseudoephedrine Benzphetamine Cocaine Diethylpropion Dopamine Sertraline Sibutramine Chlorpheniramine Diphenylpyraline Nefazodone Bupropion Chloroprocaine Escitalopram Lisdexamfetamine Ephedra MMDA 3,4-Methylenedioxymethamphetamine Fencamfamine 4-Methoxyamphetamine Dextroamphetamine Methamphetamine Nomifensine Dexmethylphenidate
Diseases
GWAS
Protein-protein Interactions		8 interactors: DRD2 GNB2L1 NEDD4 PICK1 SNCA SNTA1 STX1A TGFB1I1
Entrez ID		6531
HPRD ID		00543
Ensembl ID		ENSG00000142319
Uniprot IDs		Q01959
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Vesicle-mediated Transport Synapse Organization Regulation Of Cellular Component Organization Regulation Of Endocytosis Receptor Internalization Negative Regulation Of Signaling Negative Regulation Of Synaptic Transmission Regulation Of Sodium Ion Transport Regulation Of Membrane Potential Positive Regulation Of Transport Regulation Of Synaptic Transmission Receptor Metabolic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Ion Transport Positive Regulation Of Endocytosis Regulation Of Signaling Negative Regulation Of Transport Positive Regulation Of Synaptic Transmission Synaptic Transmission, Dopaminergic Behavioral Response To Cocaine Regulation Of Cellular Localization Regulation Of Neurotransmitter Uptake Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Positive Regulation Of Neurotransmitter Secretion Regulation Of Synaptic Transmission, Dopaminergic Positive Regulation Of Receptor Internalization Regulation Of Dopamine Secretion Regulation Of Ion Homeostasis Regulation Of Synaptic Plasticity Synaptic Transmission Regulation Of Ion Transport Monoamine Transport Dopamine Metabolic Process Regulation Of Response To Reactive Oxygen Species Vesicle-mediated Transport Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization Response To Iron Ion Positive Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Nucleotide Metabolic Process Negative Regulation Of Transporter Activity Regulation Of Synaptic Vesicle Transport Catecholamine Metabolic Process Regulation Of Cellular Response To Oxidative Stress Response To Cocaine Cell-cell Signaling Positive Regulation Of Secretion Neuromuscular Junction Development
Tagcloud ?		adra1d aminobutyric attentional caregivers catecholaminergic classes covariates departments descriptive encode ergic gaba gabaergic genotypic htr2a latent membership multivariable neurotransmission oncology rs2296972 rs2697138 rs37022 rs4815675 rs9534496 serotonergic trajectories variations