SLC6A1

Gene Name		solute carrier family 6 (neurotransmitter transporter), member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Axon
	Molecular Function	Neurotransmitter:sodium Symporter Activity Gamma-aminobutyric Acid:sodium Symporter Activity
	Biological Process	Transport Synaptic Transmission Neurotransmitter Secretion Learning Response To Toxic Substance Response To Sucrose Response To Lead Ion Positive Regulation Of Gamma-aminobutyric Acid Secretion Response To Purine-containing Compound Negative Regulation Of Synaptic Transmission, GABAergic Response To Estradiol Response To Cocaine Protein Homooligomerization Response To Calcium Ion Gamma-aminobutyric Acid Import Transmembrane Transport
Pathways		Na+/Cl- dependent neurotransmitter transporters Neurotransmitter Release Cycle Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds GABA synthesis, release, reuptake and degradation SLC-mediated transmembrane transport Transmission across Chemical Synapses Reuptake of GABA
Drugs		Tiagabine Guvacine
Diseases
GWAS		Conduct disorder (interaction) ( 18846501) Response to Vitamin E supplementation ( 22437554)
Protein-protein Interactions		1 interactors: STX1A
Entrez ID		6529
HPRD ID		00664
Ensembl ID		ENSG00000157103
Uniprot IDs		P30531
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Response To Gravity Positive Regulation Of Neurotransmitter Secretion Glutamate Secretion Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Synaptic Vesicle Transport Positive Regulation Of Membrane Potential Calcium Ion-dependent Exocytosis Vesicle Fusion Synaptic Vesicle Exocytosis Acid Secretion Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Regulation Of Neurotransmitter Secretion Regulation Of Excitatory Postsynaptic Membrane Potential Organelle Fusion Regulation Of Postsynaptic Membrane Potential Vesicle Docking Dicarboxylic Acid Transport Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission Membrane Depolarization Membrane Fusion Energy Reserve Metabolic Process Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Amino Acid Transport Neurotransmitter Transport Regulation Of Insulin Secretion Establishment Of Vesicle Localization Pathogenesis Vesicle Organization Vesicle Localization Regulation Of Peptide Hormone Secretion Regulation Of Hormone Secretion Regulation Of Membrane Potential Energy Derivation By Oxidation Of Organic Compounds Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Positive Regulation Of Secretion Establishment Of Organelle Localization Regulation Of Protein Complex Assembly Exocytosis Regulation Of Vesicle-mediated Transport
Tagcloud ?		adra1d aminobutyric attentional caregivers catecholaminergic classes covariates departments descriptive encode ergic gaba gabaergic genotypic htr2a latent membership multivariable neurotransmission oncology rs2296972 rs2697138 rs37022 rs4815675 rs9534496 serotonergic trajectories variations