RPN2

Gene Name		ribophorin II
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Autophagic Vacuole Membrane Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane
	Molecular Function	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Ribosome Binding
	Biological Process	Translation Cellular Protein Modification Process SRP-dependent Cotranslational Protein Targeting To Membrane Aging Gene Expression Protein N-linked Glycosylation Via Asparagine Response To Drug Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Translation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification SRP-dependent cotranslational protein targeting to membrane Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective MOGS causes MOGS-CDG (CDG-2b) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Defective ALG11 causes ALG11-CDG (CDG-1p)
Drugs
Diseases
GWAS		Hippocampal atrophy ( 19668339)
Protein-protein Interactions		8 interactors: ADRM1 EZH2 FBN3 NDRG1 NGFR RBBP4 RCHY1 RHOA
Entrez ID		6185
HPRD ID		01609
Ensembl ID		ENSG00000118705
Uniprot IDs		P04844
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Positive Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Axonogenesis Regulation Of Epidermis Development Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Axonogenesis Regulation Of Cell Morphogenesis Regulation Of Cell Cycle Process Positive Regulation Of Cell Development Negative Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Neurogenesis Regulation Of Proteolysis Negative Regulation Of Cell Projection Organization Regulation Of Neurogenesis Negative Regulation Of Hair Follicle Development Skeletal Muscle Satellite Cell Migration Regulation Of Axonogenesis Negative Regulation Of Cell Differentiation Negative Regulation Of Hair Cycle Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Neuron Differentiation Regulation Of Cell Development Positive Regulation Of Cell Differentiation Regulation Of Gene Expression, Epigenetic Neurotrophin TRK Receptor Signaling Pathway Apolipoprotein A-I-mediated Signaling Pathway Positive Regulation Of Neuron Projection Development Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Positive Regulation Of Spindle Checkpoint Cleavage Furrow Formation Regulation Of Protein Metabolic Process Central Nervous System Development Nervous System Development G1 To G0 Transition Protein Complex Assembly Cell Cycle Process DNA Replication-dependent Nucleosome Assembly Positive Regulation Of Cell Projection Organization Positive Regulation Of Cell Cycle Negative Regulation Of Epidermal Cell Differentiation Positive Regulation Of Cell Cycle Checkpoint Proteasome Assembly Histone H3-K27 Methylation Negative Regulation Of Neurogenesis Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		acc1 adp1 aids albicans antiretroviral candida candidiasis decades diploid divergence epidemiology fluconazole gln4 haart heterozygous immunocompromised iran iranian isolate loci mlst multilocus phylogeny polymorphic scheme sya1 typed typing vps13