P4HTM

Gene Name		prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Iron Ion Binding Calcium Ion Binding Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors L-ascorbic Acid Binding
	Biological Process	Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: GLP1R PDIA2 UBC
Entrez ID		54681
HPRD ID		17842
Ensembl ID		ENSG00000178467
Uniprot IDs		Q9NXG6
PDB IDs
Enriched GO Terms of Interacting Partners?		Energy Reserve Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Generation Of Precursor Metabolites And Energy Protein Retention In ER Lumen Viral Protein Processing Maintenance Of Protein Localization In Endoplasmic Reticulum Regulation Of Signaling Cellular Homeostasis CAMP-mediated Signaling Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Response To Stress Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Peptidyl-proline Hydroxylation Glycogen Biosynthetic Process Intracellular Transport Of Virus Activation Of Adenylate Cyclase Activity Protein Hydroxylation Cyclic-nucleotide-mediated Signaling Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Glucagon Stimulus Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Lyase Activity Negative Regulation Of ERBB Signaling Pathway Regulation Of Cellular Response To Oxidative Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Glucagon Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Adenylate Cyclase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process Positive Regulation Of CAMP Biosynthetic Process
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