PGGT1B

Gene Name		protein geranylgeranyltransferase type I, beta subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	CAAX-protein Geranylgeranyltransferase Complex
	Molecular Function	Protein Geranylgeranyltransferase Activity CAAX-protein Geranylgeranyltransferase Activity Drug Binding Zinc Ion Binding Isoprenoid Binding Peptide Binding
	Biological Process	Positive Regulation Of Cell Proliferation Protein Geranylgeranylation Response To Cytokine Positive Regulation Of Cell Cycle Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process
Pathways
Drugs		4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE GERANYLGERANYL DIPHOSPHATE 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE
Diseases
GWAS
Protein-protein Interactions		5 interactors: CDC42 GNG2 KRAS RHOB RRAS2
Entrez ID		5229
HPRD ID		03612
Ensembl ID		ENSG00000164219
Uniprot IDs		P53609
PDB IDs
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Small GTPase Mediated Signal Transduction Response To Wounding Ras Protein Signal Transduction Regulation Of Neuron Death Axon Guidance Regulation Of Cell Death Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Vascular Endothelial Growth Factor Receptor Signaling Pathway Intracellular Signal Transduction Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Small GTPase Mediated Signal Transduction Neuron Projection Development Positive Regulation Of Hair Follicle Cell Proliferation Cell Projection Morphogenesis Cell Part Morphogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Signal Transduction Actin Filament Branching Submandibular Salivary Gland Formation Neuron Development Platelet Activation Signaling Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Cell Morphogenesis Cell Communication Leukocyte Migration Positive Regulation Of Rac Protein Signal Transduction Regulation Of Neuron Apoptotic Process Neuron Differentiation Cell Projection Organization Establishment Of Golgi Localization Fc Receptor Signaling Pathway Transformed Cell Apoptotic Process Positive Regulation Of Metalloenzyme Activity Locomotion Cellular Response To Peptide Hormone Stimulus Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Cellular Response To Stimulus Muscle Cell Differentiation
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