ING4

Gene Name		inhibitor of growth family, member 4
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Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	DNA Replication Chromatin Organization Protein Acetylation Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Growth
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-protein Interactions		17 interactors: CDC34 EGLN1 EP300 HIST1H3A HIST3H3 HNRNPD HOXB9 JADE1 JADE2 KAT7 MSX1 MYC NAV2 RELA SUV39H1 TLX3 TP53
Entrez ID		51147
HPRD ID		09774
Ensembl ID		ENSG00000111653
Uniprot IDs		Q9UNL4
PDB IDs		2K1J 2M1R 2PNX 2VNF 4AFL
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Histone H4-K12 Acetylation Histone H4 Acetylation Heterocycle Metabolic Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Hypoxia Transcription, DNA-templated Cellular Response To Decreased Oxygen Levels Peptidyl-lysine Modification Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Response To Oxygen Levels Histone Acetylation Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Cellular Nitrogen Compound Metabolic Process Protein Acetylation Chromatin Modification Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Histone H3 Acetylation Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Histone Modification Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Cellular Response To Nicotine Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Anterior/posterior Pattern Specification
Tagcloud ?		aad adenovirus adopted apparently arrested bax bcl blot caspase cleaved cne differential efect g2 measure mtt nasopharyngeal obviously overexpressed p21 pe probable regulating rgd rt survivin synergies vector western