NPPC

Gene Name		natriuretic peptide C
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Secretory Granule
	Molecular Function	Receptor Binding Hormone Activity Protein Homodimerization Activity Peptide Hormone Receptor Binding
	Biological Process	Ossification Response To Hypoxia Growth Plate Cartilage Chondrocyte Differentiation Growth Plate Cartilage Chondrocyte Proliferation CGMP Biosynthetic Process Receptor Guanylyl Cyclase Signaling Pathway Negative Regulation Of Cell Proliferation Post-embryonic Development Regulation Of CAMP Metabolic Process Regulation Of CGMP Metabolic Process Positive Regulation Of CGMP Biosynthetic Process Regulation Of Multicellular Organism Growth Response To Drug Single Organism Reproductive Process Response To Ethanol Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Vasodilation Regulation Of Smooth Muscle Cell Proliferation Regulation Of Blood Vessel Size Negative Regulation Of DNA Metabolic Process Negative Regulation Of Meiotic Cell Cycle Negative Regulation Of Oocyte Maturation
Pathways
Drugs
Diseases
GWAS		Height ( 20881960 19570815 18391951)
Protein-protein Interactions		4 interactors: MME NPR1 NPR2 NPR3
Entrez ID		4880
HPRD ID		08975
Ensembl ID
Uniprot IDs		E5LCN7 P23582
PDB IDs		1JDP
Enriched GO Terms of Interacting Partners?		Regulation Of Blood Pressure Blood Circulation Receptor Guanylyl Cyclase Signaling Pathway Positive Regulation Of Urine Volume CGMP Biosynthetic Process CGMP Metabolic Process Cyclic Purine Nucleotide Metabolic Process Negative Regulation Of Smooth Muscle Cell Proliferation Cyclic Nucleotide Biosynthetic Process Cyclic Nucleotide Metabolic Process Renal System Process Regulation Of Smooth Muscle Cell Proliferation Body Fluid Secretion Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Cellular Response To UV-A Negative Regulation Of Oocyte Maturation Negative Regulation Of Oocyte Development Osteoclast Proliferation Creatinine Metabolic Process Ribonucleotide Metabolic Process Response To UV-A Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Pancreatic Juice Secretion Cellular Response To UV-B Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Angiotensin Maturation Intracellular Signal Transduction Regulation Of Angiotensin Metabolic Process Positive Regulation Of Renal Sodium Excretion Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Response To UV-B Replicative Senescence Positive Regulation Of CGMP Biosynthetic Process Positive Regulation Of Nitric-oxide Synthase Activity Beta-amyloid Metabolic Process Positive Regulation Of CGMP Metabolic Process Skeletal System Development Nucleotide Metabolic Process Regulation Of Body Fluid Levels Cellular Response To Cytokine Stimulus Small Molecule Metabolic Process Regulation Of Renal Sodium Excretion Negative Regulation Of Adenylate Cyclase Activity Regulation Of CGMP Biosynthetic Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Negative Regulation Of Lyase Activity Regulation Of Osteoblast Proliferation
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