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NFKBIL1
Gene Name
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Intermediate Filament Cytoskeleton
Molecular Function
Protein Binding
Biological Process
I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Toll-like Receptor Signaling Pathway
Cytoplasmic Sequestering Of Transcription Factor
Cellular Response To Lipopolysaccharide
Pathways
Drugs
Diseases
GWAS
Crohn's disease (
23128233
)
Neonatal lupus (
20662065
)
Protein-protein Interactions
4 interactors:
ADIPOR1
C2orf88
CASP10
CLEC18C
Entrez ID
4795
HPRD ID
07043
Ensembl ID
ENSG00000204498
Uniprot IDs
A8K778
Q5STV6
Q9UBC1
PDB IDs
Enriched GO Terms of Interacting Partners
?
Leptin-mediated Signaling Pathway
Adiponectin-activated Signaling Pathway
Cellular Response To Leptin Stimulus
Response To Leptin
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Insulin Receptor Signaling Pathway
Positive Regulation Of Signal Transduction
Positive Regulation Of JAK-STAT Cascade
Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Intracellular Signal Transduction
Fatty Acid Oxidation
Lipid Oxidation
Regulation Of Cellular Response To Insulin Stimulus
Regulation Of JAK-STAT Cascade
Hormone-mediated Signaling Pathway
Negative Regulation Of Cell Growth
Regulation Of Signal Transduction
Tagcloud
?
6p21
correspond
cpg
distant
dnase
dysregulation
enhancer
exon
hek293t
hypersensitive
intergenic
island
jurkat
k4
localize
locus
lta
ltb
lymphoblastoid
lymphotoxin
peaks
polypeptide
spanning
stimulatory
tri
u937
upstream
usf