INSM1

Gene Name		insulinoma-associated 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcriptional Repressor Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Cyclin Binding Chromatin DNA Binding Histone Deacetylase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Phosphorylation Type B Pancreatic Cell Differentiation Pancreatic A Cell Differentiation Type B Pancreatic Cell Development Noradrenergic Neuron Development Transcription, DNA-templated Cell Cycle Negative Regulation Of Cell Proliferation Regulation Of Gene Expression Endocrine Pancreas Development Norepinephrine Biosynthetic Process Regulation Of Protein Complex Assembly Positive Regulation Of Cell Differentiation Transdifferentiation Adrenal Chromaffin Cell Differentiation Sympathetic Ganglion Development Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Regulation of beta-cell development Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CCND1 MPP3 SORBS1 TUBB3
Entrez ID		3642
HPRD ID		02480
Ensembl ID		ENSG00000173404
Uniprot IDs		Q01101
PDB IDs		2LV2 3ZMS
Enriched GO Terms of Interacting Partners?
Tagcloud ?		acetyl akt ar42j beta2 conclude elevation enhance enhancer enhances enhancing extra h4 inr interrupts islet ly294002 modification neurod nkx6 pancreas pi3k possesses proline rack1 regulators repressor rich terminus trans