HLA-DOA

Gene Name		major histocompatibility complex, class II, DO alpha
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Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Endosome Membrane Integral Component Of Membrane MHC Class II Protein Complex
	Molecular Function	MHC Class II Protein Complex Binding MHC Class II Receptor Activity
	Biological Process	Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response Signal Transduction Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of T Cell Differentiation
Pathways		MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Asthma ( 21804548) Platelet counts ( 22139419) Wegener's granulomatosis ( 23740775)
Protein-protein Interactions		2 interactors: HLA-DMA REL
Entrez ID		3111
HPRD ID		00837
Ensembl ID		ENSG00000204252
Uniprot IDs		B4DW77 P06340
PDB IDs		4I0P
Enriched GO Terms of Interacting Partners?		Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly Positive Thymic T Cell Selection Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process Thymic T Cell Selection Chaperone Mediated Protein Folding Requiring Cofactor Positive T Cell Selection Immune Response NIK/NF-kappaB Signaling T Cell Selection Positive Regulation Of Interleukin-12 Production
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