IL37

Gene Name		interleukin 37
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Cytokine Activity Interleukin-1 Receptor Binding
	Biological Process	Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: CASP1 CASP4 IL18BP IL18R1 SMAD3
Entrez ID		27178
HPRD ID		05695
Ensembl ID		ENSG00000125571
Uniprot IDs		Q9NZH6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production T-helper 1 Type Immune Response Regulation Of Inflammatory Response Positive Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Transport Positive Regulation Of Cytokine Production Regulation Of Interleukin-1 Beta Production Immune Response Execution Phase Of Apoptosis Regulation Of Cytokine Production Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Transcription Factor Import Into Nucleus Activation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Protein Import Into Nucleus Regulation Of Protein Transport Zymogen Activation Cellular Response To Organic Substance Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Transforming Growth Factor Beta3 Production Interleukin-18-mediated Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Response To Other Organism Positive Regulation Of Transport Positive Regulation Of Endopeptidase Activity Response To Biotic Stimulus Immune System Process Regulation Of Protein Localization Positive Regulation Of Peptidase Activity Cellular Response To Interleukin-18 Mitochondrial Depolarization Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Organic Substance Evasion Or Tolerance Of Host Defenses By Virus Response To Interleukin-18 Positive Regulation Of Interleukin-1 Alpha Secretion Apoptotic Process Regulation Of Protein Localization To Nucleus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Programmed Cell Death Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Cellular Localization Regulation Of Nucleocytoplasmic Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly
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