FCGR3B

Gene Name		Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	IgG Binding
	Biological Process	Immune Response
Pathways
Drugs		Cetuximab Etanercept Intravenous Immunoglobulin Adalimumab Abciximab Gemtuzumab ozogamicin Trastuzumab Rituximab Basiliximab Muromonab Ibritumomab Tositumomab Alemtuzumab Alefacept Efalizumab Natalizumab Palivizumab Daclizumab Bevacizumab
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		2 interactors: APCS IGHG1
Entrez ID		2215
HPRD ID		09951
Ensembl ID		ENSG00000162747
Uniprot IDs		M9MML6 O75015
PDB IDs		1E4J 1E4K 1FNL 1T83 1T89
Enriched GO Terms of Interacting Partners?		Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Negative Regulation Of Exo-alpha-sialidase Activity Negative Regulation Of Monocyte Differentiation Negative Regulation Of Glycoprotein Metabolic Process Chaperone-mediated Protein Complex Assembly Regulation Of Monocyte Differentiation Negative Regulation Of Acute Inflammatory Response Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Regulation Of Viral Entry Into Host Cell Interaction With Symbiont Immune Response Regulation Of Immune System Process Defense Response Acute-phase Response Negative Regulation Of Myeloid Leukocyte Differentiation Negative Regulation Of Wound Healing Regulation Of Acute Inflammatory Response Negative Regulation Of Viral Process Acute Inflammatory Response Negative Regulation Of Myeloid Cell Differentiation Immune System Process Negative Regulation Of Inflammatory Response Regulation Of Myeloid Leukocyte Differentiation Complement Activation, Classical Pathway Regulation Of Wound Healing Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Regulation Of Viral Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Protein Activation Cascade Regulation Of Myeloid Cell Differentiation Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Humoral Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Negative Regulation Of Locomotion Response To Stress Phagocytosis Leukocyte Mediated Immunity Fc Receptor Signaling Pathway Adaptive Immune Response Regulation Of Inflammatory Response Immune Response-activating Cell Surface Receptor Signaling Pathway Protein Folding Cellular Protein Complex Assembly
Tagcloud ?		advantages applicability carry cloned cnas cnvs comparable competitive competitors copy cost erbb2 invaluable issues limitations mrcpcr nci numbers panel paralog prt reproducibility requirement responsiveness shorter solve utilizing variations