EPHA5

Gene Name		EPH receptor A5
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Gene Ontology Annotations	Cellular Component	Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Axon Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Ephrin Receptor Activity GPI-linked Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity ATP Binding
	Biological Process	Axon Guidance Peptidyl-tyrosine Phosphorylation CAMP-mediated Signaling Hippocampus Development Regulation Of Rac GTPase Activity Positive Regulation Of CREB Transcription Factor Activity Regulation Of Actin Cytoskeleton Organization Ephrin Receptor Signaling Pathway Neuron Development Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways		EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS		HIV-1 viral setpoint ( 22174851)
Protein-protein Interactions		6 interactors: EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 NEDD4
Entrez ID		2044
HPRD ID		02474
Ensembl ID		ENSG00000145242
Uniprot IDs		B7ZKJ3 B7ZKW7 F8VP57 F8W9W0 P54756 Q59FT4
PDB IDs		2R2P 4ET7
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Neuron Projection Development Neuron Development Axon Guidance Neuron Differentiation Cell Projection Organization Locomotion Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Generation Of Neurons Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurogenesis Cell Morphogenesis Involved In Differentiation Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Nervous System Development Cell Morphogenesis Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Cell Differentiation Response To External Stimulus Cell-cell Signaling System Development Osteoclast Differentiation Multicellular Organismal Development Anatomical Structure Development Bone Remodeling Signal Transduction Regulation Of Dendrite Morphogenesis Developmental Process Signaling Cell Communication Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Dendrite Development Tissue Remodeling Myeloid Leukocyte Differentiation Cellular Response To Stimulus Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Dendritic Spine Morphogenesis Endocardial Cushion To Mesenchymal Transition Involved In Heart Valve Formation Mesenchyme Development Regulation Of Peptidyl-tyrosine Phosphorylation
Tagcloud ?		aurka aurkb bioinformatics cdkn2a copy custom describing flt4 frameshift insertions interrogating kdm6a leiomyosarcomas locally losses map2k4 multiplexed nf1 ngs notch1 pdgfrb pik3ca pipeline rationale rb1 sarcomas soft stratification targetable