SIGMAR1

Gene Name		sigma non-opioid intracellular receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Membrane Lipid Particle Integral Component Of Plasma Membrane Integral Component Of Membrane Cell Junction Growth Cone
	Molecular Function	Opioid Receptor Activity Drug Binding
	Biological Process	Lipid Transport Nervous System Development Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process
Pathways
Drugs		Dextromethorphan Naltrexone
Diseases
GWAS
Protein-protein Interactions		3 interactors: ANK2 ITPR3 PDZD11
Entrez ID		10280
HPRD ID		03580
Ensembl ID		ENSG00000147955
Uniprot IDs		A2A3U5 B4DR71 Q99720
PDB IDs
Enriched GO Terms of Interacting Partners?		Second-messenger-mediated Signaling Protein Localization To Plasma Membrane Protein Localization To T-tubule Protein Localization To M-band T-tubule Organization Plasma Membrane Organization Ion Transport Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Calcium Ion Transport Protein Localization To Basolateral Plasma Membrane Membrane Depolarization During SA Node Cell Action Potential Establishment Of Localization In Cell SA Node Cell Action Potential Maintenance Of Epithelial Cell Apical/basal Polarity Sensory Perception Of Sweet Taste Protein Localization To Membrane Maintenance Of Apical/basal Cell Polarity Sensory Perception Of Umami Taste Cellular Metal Ion Homeostasis Regulation Of Cardiac Muscle Cell Membrane Potential Endomembrane System Organization Atrial Cardiac Muscle Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Communication Atrial Cardiac Muscle Cell To AV Node Cell Communication Cellular Cation Homeostasis Cellular Ion Homeostasis Cellular Localization Response To Methylmercury Metal Ion Homeostasis Sarcoplasmic Reticulum Calcium Ion Transport Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Pantothenate Metabolic Process Maintenance Of Cell Polarity Biotin Metabolic Process Cellular Chemical Homeostasis Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ion Homeostasis Cell-cell Signaling Involved In Cardiac Conduction Positive Regulation Of Potassium Ion Transmembrane Transport Paranodal Junction Assembly Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Inositol Phosphate-mediated Signaling Protein Localization To Cell Surface Ventricular Cardiac Muscle Cell Action Potential Cellular Homeostasis Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Atrial Septum Development Regulation Of Heart Rate By Cardiac Conduction
Tagcloud ?		became chaperones chronologically cytoplasm degrades epoxomicin exportin harboring hela huntingtin huntington inclusion inclusions insolubilized lc3 leptomycin machinery misfolded ni nis nucleus p62 participate polyglutamine proteasome shuttle sirna unchanged