MEF2B

Gene Name		myocyte enhancer factor 2B
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cell Junction
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Histone Deacetylase Binding Protein Dimerization Activity
	Biological Process	Transcription, DNA-templated Muscle Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: CABIN1 HDAC4
Entrez ID		100271849
HPRD ID		19467
Ensembl ID		ENSG00000213999
Uniprot IDs		Q02080
PDB IDs		1N6J 1TQE
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glycolytic Process Peptidyl-lysine Deacetylation Response To Denervation Involved In Regulation Of Muscle Adaptation Chromatin Modification Response To Inactivity Chromatin Organization Negative Regulation Of Myotube Differentiation Positive Regulation Of Protein Sumoylation Regulation Of Skeletal Muscle Fiber Development Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Protein Sumoylation Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Chromosome Organization Histone H4 Deacetylation Regulation Of Glycolytic Process Cardiac Muscle Hypertrophy Osteoblast Development Muscle Hypertrophy Histone H3 Deacetylation DNA Replication-independent Nucleosome Assembly Histone H3-K9 Modification Negative Regulation Of Muscle Cell Differentiation Negative Regulation Of Osteoblast Differentiation Regulation Of Myotube Differentiation Histone Deacetylation Regulation Of Skeletal Muscle Tissue Development Protein Deacetylation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Cardiac Muscle Contraction Negative Regulation Of Ossification Response To Interleukin-1 Regulation Of Striated Muscle Contraction Calcium-mediated Signaling Regulation Of Striated Muscle Cell Differentiation B Cell Differentiation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleosome Assembly Regulation Of Osteoblast Differentiation Chromatin Assembly Regulation Of Striated Muscle Tissue Development Osteoblast Differentiation Second-messenger-mediated Signaling Nucleosome Organization Regulation Of Protein Binding Regulation Of Carbohydrate Metabolic Process Regulation Of Muscle Cell Differentiation Chromatin Assembly Or Disassembly Regulation Of Muscle Contraction B Cell Activation
Tagcloud ?		aberrations additional advances approaches biological closely contribute crebbp ep300 epha7 expected ezh2 fl follicular genetic hallmark hand individuals lymphoma microenvironment mll2 pathogenesis recognized recurrent technology tnfrsf14 translocation understanding unique