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Search Results for: SLU7

20 interactions involving SLU7 - SLU7 homolog, splicing factor found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
ARHGEF5 Rho guanine nucleotide exchange factor 5
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • G alpha (12/13) signalling events
BAG2 BAG cochaperone 2
  • Regulation of HSF1-mediated heat shock response
CCDC85B coiled-coil domain containing 85B
CEP70 centrosomal protein 70
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
GOLGA2 golgin A2
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • Golgi Cisternae Pericentriolar Stack Reorganization
  • COPII-mediated vesicle transport
  • COPI-mediated anterograde transport
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
GTF2I general transcription factor IIi
JMJD6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase
  • HDMs demethylate histones
KDM1A lysine demethylase 1A
  • HDACs deacetylate histones
  • HDMs demethylate histones
  • Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
  • Regulation of PTEN gene transcription
  • Estrogen-dependent gene expression
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • Factors involved in megakaryocyte development and platelet production
KRT40 keratin 40
  • Keratinization
  • Formation of the cornified envelope
LMNA lamin A/C
  • XBP1(S) activates chaperone genes
  • Signaling by BRAF and RAF fusions
  • Restrictive dermopathy
  • Emery-Dreifuss muscular dystrophy
  • Dilated cardiomyopathy (DCM)
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
  • Mandibuloacral dysplasia
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Limb-girdle muscular dystrophy (LGMD)
  • Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
  • Hutchinson-Gilford progeria syndrome
LZTS2 leucine zipper tumor suppressor 2
NSD3 nuclear receptor binding SET domain protein 3
  • PKMTs methylate histone lysines
PCBP2 poly(rC) binding protein 2
  • mRNA Splicing - Major Pathway
  • Processing of Capped Intron-Containing Pre-mRNA
  • Negative regulators of DDX58/IFIH1 signaling
PPIG peptidylprolyl isomerase G
  • L-Proline
PPIL3 peptidylprolyl isomerase like 3
  • mRNA Splicing - Major Pathway
PRMT5 protein arginine methyltransferase 5
  • snRNP Assembly
  • RMTs methylate histone arginines
  • Regulation of TP53 Activity through Methylation
PRMT6 protein arginine methyltransferase 6
  • RMTs methylate histone arginines
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
THAP1 THAP domain containing 1
  • Primary torsion dystonia (PTD)
ZBED8 zinc finger BED-type containing 8
ZCCHC10 zinc finger CCHC-type containing 10