SLU7 and GTF2I

Number of citations of the paper that reports this interaction (PubMedID 18662664)
8

Data Source:
BioGRID (pull down)

		SLU7	GTF2I
Description		SLU7 homolog, splicing factor	general transcription factor IIi
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Catalytic Step 2 Spliceosome	Cell Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Intracellular Protein Transport RNA Splicing MRNA 3'-end Processing Cellular Response To Heat	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Angiogenesis Negative Regulation Of Cytosolic Calcium Ion Concentration
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Common carotid intima-media thickness ( 29206233)	Atrial fibrillation ( 30061737 29892015) C-reactive protein levels ( 30388399) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Diastolic blood pressure ( 30224653) Heel bone mineral density ( 30598549) Menarche (age at onset) ( 25231870) SjÃ¶gren's syndrome ( 24097066 27503288) Systemic lupus erythematosus ( 28714469)
Interacting Genes		20 interacting genes: ARHGEF5 BAG2 CCDC85B CEP70 GOLGA2 GTF2I JMJD6 KDM1A KRT40 LMNA LZTS2 NSD3 PCBP2 PPIG PPIL3 PRMT5 PRMT6 THAP1 ZBED8 ZCCHC10	39 interacting genes: AP2B1 AP4S1 ATF6 BCL2L11 BTK C4BPA CALM1 DNMT3L DPY30 GCC1 HDAC3 JAK2 LSM8 MAP3K3 MAPK12 MAPK3 MTUS2 MYC NFKB2 PIAS2 PJA1 POU2AF1 PRKG1 PRRX1 SLU7 SMAD2 SNRPN SRC SRF STAT1 STAT3 TAB2 TRAF6 UBC UBE2I USF1 YY1 ZBTB17 ZMYM3
Entrez ID		10569	2969
HPRD ID		12074	03399
Ensembl ID		ENSG00000164609	ENSG00000263001
Uniprot IDs		O95391	A8K9W7 P78347 Q499G6 X5D2J9 X5D939 X5DNP5 X5DR09
PDB IDs		5XJC 6ICZ 6QDV	2D9B 2DN4 2ED2 2EJE
Enriched GO Terms of Interacting Partners?
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