Search Results for: NEU1

18 interactions involving NEU1 - neuraminidase 1 found:

Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
CDC42SE2 CDC42 small effector 2
CREB3 cAMP responsive element binding protein 3
  • CREB3 factors activate genes
  • CREB3 factors activate genes
CTSA cathepsin A
  • Glycosphingolipid metabolism
  • MHC class II antigen presentation
  • Sialic acid metabolism
  • Defective NEU1 causes sialidosis
  • Neutrophil degranulation
  • Galactosialidosis
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
  • Eukaryotic Translation Elongation
  • Eukaryotic Translation Elongation
  • Peptide chain elongation
  • HSF1 activation
  • Neutrophil degranulation
  • Protein methylation
  • Chaperone Mediated Autophagy
  • Zinc
  • Guanosine-5'-Diphosphate
  • Copper
  • Artenimol
ERRFI1 ERBB receptor feedback inhibitor 1
GLB1 galactosidase beta 1
  • Glycosphingolipid metabolism
  • Keratan sulfate degradation
  • HS-GAG degradation
  • MPS IV - Morquio syndrome B
  • Sialic acid metabolism
  • Defective NEU1 causes sialidosis
  • Neutrophil degranulation
  • Galactosialidosis
  • GM1 gangliosidosis
  • Mucopolysaccharidosis type IV (MPS4), including: Morquio syndrome A (MPS4A); Morquio syndrome B (MPS4B)
IGF1 insulin like growth factor 1
  • Platelet degranulation
  • Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
  • IRS-related events triggered by IGF1R
  • SHC-related events triggered by IGF1R
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Synthesis, secretion, and deacylation of Ghrelin
  • N,N-bis(3-(D-gluconamido)propyl)deoxycholamide
  • N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate
  • Malignant pleural mesothelioma
  • Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
JUNB JunB proto-oncogene, AP-1 transcription factor subunit
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Interleukin-4 and Interleukin-13 signaling
  • NGF-stimulated transcription
KCNA2 potassium voltage-gated channel subfamily A member 2
  • Voltage gated Potassium channels
  • Dalfampridine
KCNA4 potassium voltage-gated channel subfamily A member 4
  • Voltage gated Potassium channels
  • Arginineamide
  • Dalfampridine
LIG4 DNA ligase 4
  • 2-LTR circle formation
  • Nonhomologous End-Joining (NHEJ)
  • DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
LMNA lamin A/C
  • XBP1(S) activates chaperone genes
  • Signaling by BRAF and RAF fusions
  • Restrictive dermopathy
  • Emery-Dreifuss muscular dystrophy
  • Dilated cardiomyopathy (DCM)
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
  • Mandibuloacral dysplasia
  • Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
  • Limb-girdle muscular dystrophy (LGMD)
  • Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy
  • Hutchinson-Gilford progeria syndrome
MAF MAF bZIP transcription factor
  • RUNX2 regulates osteoblast differentiation
  • Multiple myeloma
MSH5 mutS homolog 5
  • Meiotic recombination
NFYA nuclear transcription factor Y subunit alpha
  • PPARA activates gene expression
  • Activation of gene expression by SREBF (SREBP)
  • Activation of gene expression by SREBF (SREBP)
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • ATF6 (ATF6-alpha) activates chaperone genes
  • ATF6 (ATF6-alpha) activates chaperone genes
  • FOXO-mediated transcription of cell death genes
NOTCH4 notch receptor 4
  • Pre-NOTCH Processing in the Endoplasmic Reticulum
  • Pre-NOTCH Transcription and Translation
  • Pre-NOTCH Processing in Golgi
  • Pre-NOTCH Processing in Golgi
  • Notch-HLH transcription pathway
  • Defective LFNG causes SCDO3
  • NOTCH4 Intracellular Domain Regulates Transcription
  • NOTCH4 Intracellular Domain Regulates Transcription
  • NOTCH4 Activation and Transmission of Signal to the Nucleus
  • NOTCH4 Activation and Transmission of Signal to the Nucleus
  • Negative regulation of NOTCH4 signaling
  • Negative regulation of NOTCH4 signaling
PBX2 PBX homeobox 2
SLC17A2 solute carrier family 17 member 2