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Search Results for: EXOSC2

27 interactions involving EXOSC2 - exosome component 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13
  • Defective B3GALTL causes Peters-plus syndrome (PpS)
  • O-glycosylation of TSR domain-containing proteins
  • Thrombotic thrombocytopenic purpura; Moschcowitz disease; Schulman-Upshaw syndrome
AMBP alpha-1-microglobulin/bikunin precursor
  • Scavenging of heme from plasma
  • Human Serum Albumin
ANGPTL2 angiopoietin like 2
CACFD1 calcium channel flower domain containing 1
COLEC12 collectin subfamily member 12
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Scavenging by Class A Receptors
DIS3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC4 exosome component 4
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC5 exosome component 5
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC6 exosome component 6
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC7 exosome component 7
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC8 exosome component 8
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
EXOSC9 exosome component 9
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • mRNA decay by 3' to 5' exoribonuclease
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Major pathway of rRNA processing in the nucleolus and cytosol
FBXW2 F-box and WD repeat domain containing 2
  • Association of TriC/CCT with target proteins during biosynthesis
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
  • O-linked glycosylation of mucins
KHSRP KH-type splicing regulatory protein
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • KSRP (KHSRP) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • Resveratrol
  • Artenimol
KIFBP kinesin family binding protein
  • Goldberg-Shprintzen megacolon syndrome; Goldberg-Shprintzen syndrome (GOSHS)
  • Polymicrogyria; Bilateral frontal polymicrogyria (BFP); Bilateral frontoparietal polymicrogyria (BFPP); Bilateral perisylvian polymicrogyria (BPP); Bilateral parasagittal parieto-occipital polymicrogyria (BPOP); Bilateral generalised polymicrogyria (BGP); Unilateral Polymicrogyria (ULP)
MPP6 membrane palmitoylated protein 6
MRPL48 mitochondrial ribosomal protein L48
  • Mitochondrial translation initiation
  • Mitochondrial translation elongation
  • Mitochondrial translation elongation
  • Mitochondrial translation termination
MTREX Mtr4 exosome RNA helicase
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • mRNA Splicing - Major Pathway
MTX2 metaxin 2
  • Mitochondrial protein import
  • Cristae formation
NCS1 neuronal calcium sensor 1
  • Calcium Citrate
  • Calcium Phosphate
NELFB negative elongation factor complex member B
  • Formation of RNA Pol II elongation complex
  • Formation of the Early Elongation Complex
  • Formation of HIV elongation complex in the absence of HIV Tat
  • Formation of the HIV-1 Early Elongation Complex
  • Formation of HIV-1 elongation complex containing HIV-1 Tat
  • Formation of HIV-1 elongation complex containing HIV-1 Tat
  • Pausing and recovery of Tat-mediated HIV elongation
  • Abortive elongation of HIV-1 transcript in the absence of Tat
  • Tat-mediated HIV elongation arrest and recovery
  • Tat-mediated elongation of the HIV-1 transcript
  • HIV elongation arrest and recovery
  • Pausing and recovery of HIV elongation
  • RNA Polymerase II Pre-transcription Events
  • TP53 Regulates Transcription of DNA Repair Genes
  • RNA Polymerase II Transcription Elongation
  • NTRK3 as a dependence receptor
RNF8 ring finger protein 8
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
ST6GALNAC1 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
  • Sialic acid metabolism
UPF1 UPF1 RNA helicase and ATPase
  • Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
VCAM1 vascular cell adhesion molecule 1
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Integrin cell surface interactions
  • Interleukin-4 and Interleukin-13 signaling
  • Interferon gamma signaling
  • Ethanol
  • Carvedilol
  • Succinobucol
ZNF408 zinc finger protein 408