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Search Results for: CHMP2A

21 interactions involving CHMP2A - charged multivesicular body protein 2A found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
CHD3 chromodomain helicase DNA binding protein 3
  • HDACs deacetylate histones
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • SUMOylation of chromatin organization proteins
  • Regulation of TP53 Activity through Acetylation
  • RNA Polymerase I Transcription Initiation
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
CHMP3 charged multivesicular body protein 3
  • Budding and maturation of HIV virion
  • Macroautophagy
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • HCMV Late Events
  • Late endosomal microautophagy
  • Sealing of the nuclear envelope (NE) by ESCRT-III
CYP4F2 cytochrome P450 family 4 subfamily F member 2
  • Fatty acids
  • Miscellaneous substrates
  • Eicosanoids
  • Synthesis of Leukotrienes (LT) and Eoxins (EX)
  • Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
DOCK8 dedicator of cytokinesis 8
  • Factors involved in megakaryocyte development and platelet production
  • Non-syndromic autosomal dominant mental retardation
E2F4 E2F transcription factor 4
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
  • G0 and Early G1
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
  • Cyclin E associated events during G1/S transition
  • G1/S-Specific Transcription
  • G1/S-Specific Transcription
  • Cyclin D associated events in G1
  • Cyclin A:Cdk2-associated events at S phase entry
EIF2B5 eukaryotic translation initiation factor 2B subunit epsilon
  • Recycling of eIF2:GDP
  • Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
ITGA5 integrin subunit alpha 5
  • Elastic fibre formation
  • Fibronectin matrix formation
  • Cell surface interactions at the vascular wall
  • Integrin cell surface interactions
  • Integrin cell surface interactions
  • Signal transduction by L1
  • RUNX2 regulates genes involved in cell migration
  • Resveratrol
KERA keratocan
  • Keratan sulfate biosynthesis
  • Keratan sulfate degradation
  • Defective CHST6 causes MCDC1
  • Defective ST3GAL3 causes MCT12 and EIEE15
  • Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
  • Cornea plana congenita
MAPKAPK3 MAPK activated protein kinase 3
  • p38MAPK events
  • Oxidative Stress Induced Senescence
  • VEGFA-VEGFR2 Pathway
  • activated TAK1 mediates p38 MAPK activation
  • 2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
  • 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
MITD1 microtubule interacting and trafficking domain containing 1
NCOA1 nuclear receptor coactivator 1
  • RORA activates gene expression
  • BMAL1:CLOCK,NPAS2 activates circadian gene expression
  • Recycling of bile acids and salts
  • Synthesis of bile acids and bile salts
  • Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
  • Synthesis of bile acids and bile salts via 27-hydroxycholesterol
  • PPARA activates gene expression
  • PPARA activates gene expression
  • Endogenous sterols
  • Transcriptional activation of mitochondrial biogenesis
  • Activation of gene expression by SREBF (SREBP)
  • HATs acetylate histones
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • SUMOylation of transcription cofactors
  • Regulation of lipid metabolism by PPARalpha
  • Circadian Clock
  • Estrogen-dependent gene expression
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
  • Genistein
  • Corticosterone
  • 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL
  • 3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1-NAPHTHONITRILE
  • (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
  • [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
  • 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL
  • N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE
  • 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL
  • 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
  • 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE
  • 2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID
  • 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE
  • 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL
  • (1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol
  • (5BETA)-PREGNANE-3,20-DIONE
  • Indeglitazar
  • (8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid
  • Myristic acid
  • 1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)
  • Aleglitazar
NOL4 nucleolar protein 4
SLC25A1 solute carrier family 25 member 1
  • Gluconeogenesis
  • Fatty acyl-CoA biosynthesis
STAMBP STAM binding protein
  • Metalloprotease DUBs
TGFB3 transforming growth factor beta 3
  • Platelet degranulation
  • Molecules associated with elastic fibres
  • ECM proteoglycans
  • 1,4-Diethylene Dioxide
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
  • Graft-versus-host disease
  • Ossification of the posterior longitudinal ligament of spine (OPLL)
  • Allograft rejection
  • Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate
UFD1 ubiquitin recognition factor in ER associated degradation 1
  • Translesion Synthesis by POLH
  • Ub-specific processing proteases
USP54 ubiquitin specific peptidase 54
USP8 ubiquitin specific peptidase 8
  • Downregulation of ERBB2:ERBB3 signaling
  • Regulation of FZD by ubiquitination
  • Ub-specific processing proteases
  • Negative regulation of MET activity
VPS4A vacuolar protein sorting 4 homolog A
  • Budding and maturation of HIV virion
  • Endosomal Sorting Complex Required For Transport (ESCRT)
  • HCMV Late Events
  • Sealing of the nuclear envelope (NE) by ESCRT-III
VPS4B vacuolar protein sorting 4 homolog B
  • Budding and maturation of HIV virion
  • Endosomal Sorting Complex Required For Transport (ESCRT)
ZNF32 zinc finger protein 32