MAFB and HOXD12

Number of citations of the paper that reports this interaction (PubMedID 11036080)
12

Data Source:
BioGRID (pull down)

		MAFB	HOXD12
Description		MAF bZIP transcription factor B	homeobox D12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex	Nuclear Chromatin Transcription Factor Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Segment Specification Sensory Organ Development Respiratory Gaseous Exchange Rhombomere 5 Development Rhombomere 6 Development Abducens Nerve Formation T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Thymus Development	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Embryonic Digit Morphogenesis
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Birth weight ( 31043758 27680694) Bone mineral density (hip) ( 30172743) Cholesterol, total ( 24097068 25961943 20686565) Cleft lip with or without cleft palate ( 28054174) Cognitive decline rate in late mild cognitive impairment ( 26252872) Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) ( 21221126) Dupuytren's disease ( 28886342 21732829) Height ( 25282103) LDL cholesterol ( 24097068 19060906 25961943 20686565) LDL cholesterol levels ( 28334899) Metabolite levels (lipoprotein measures) ( 27005778) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Obesity-related traits ( 23251661) Orofacial clefts ( 28054174) Paneth cell defects in Crohn's disease ( 28352666) Plasma parathyroid hormone levels ( 30134803) QT interval (ambient particulate matter interaction) ( 28749367) Response to TNF antagonist treatment ( 18615156) Serum total protein level ( 29403010) Total body bone mineral density ( 29304378)	Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Male-pattern baldness ( 28196072)
Interacting Genes		11 interacting genes: ATF4 BACH1 DDB1 FOS FOSL1 HOXD12 JUN MAF ZDHHC2 ZFP64 ZWINT	8 interacting genes: CREBBP MAF MAFB MAFF MAFG MAFK MEIS1 TRAF1
Entrez ID		9935	3238
HPRD ID		07129	00871
Ensembl ID		ENSG00000204103	ENSG00000170178
Uniprot IDs		Q9Y5Q3	P35452
PDB IDs
Enriched GO Terms of Interacting Partners?
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