TMCC2 and ZNF250

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TMCC2	ZNF250
Description		transmembrane and coiled-coil domain family 2	zinc finger protein 250
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Integral Component Of Membrane	Nucleus
	Molecular Function	Protein Binding	DNA Binding Metal Ion Binding
	Biological Process	Amyloid Precursor Protein Metabolic Process	Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 22139419 24026423 19820697 27863252) Platelet count ( 22139419) Platelet distribution width ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		29 interacting genes: AKT1 AMOTL2 APP CCDC33 CDR2 CFAP206 DIP2A DPY30 EIF4E2 FAM161A FAM74A4 FAM90A1 FBF1 HGS HNRNPLL HSPD1 IQUB KAT5 PRPF31 PTOV1 RHOXF2 TLE5 UBA1 WT1-AS ZNF250 ZNF417 ZNF581 ZNF587 ZNF688	47 interacting genes: BEGAIN CARD9 CCDC102B CCDC136 CCDC85B CDCA7L CEP44 DPPA2 DVL2 FAM124A GMCL1 GNPTAB GOLGA2 HEXIM2 HOOK1 HOOK2 KASH5 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 LDOC1 LZTS2 MAGOHB MID2 MTUS2 NINL PLEKHF2 PRPF31 SSX2IP SYNE4 TFF1 TMCC2 TNNT1 TNS2 TRAF1 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB8A ZC4H2 ZNF165 ZNF175 ZNF460 ZNF473
Entrez ID		9911	58500
HPRD ID		11040	15758
Ensembl ID		ENSG00000133069	ENSG00000196150
Uniprot IDs		A0A0C4DFR1 O75069 Q8IW47	B3KNS9 P15622
PDB IDs
Enriched GO Terms of Interacting Partners?
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