FCHSD2 and CCDC158

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FCHSD2	CCDC158
Description		FCH and double SH3 domains 2	coiled-coil domain containing 158
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Cell Junction Neuromuscular Junction Recycling Endosome Stereocilium Shaft
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Multi-organism Membrane Organization Clathrin-dependent Endocytosis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Crohn's disease ( 23850713 23266558) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Serum total protein level ( 29403010) Systemic lupus erythematosus ( 26663301)	Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31015462)
Interacting Genes		26 interacting genes: ABCF3 C2orf73 C9orf78 CASK CCDC158 CCDC85B CCT2 CFAP36 CHKA DAPP1 FAM9B HGS HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 MSL1 MTUS2 PDE4DIP SH3BGR SRP72 VCPIP1 WAS WASL	6 interacting genes: C1orf216 FCHSD2 GPSM1 NAGK SGF29 SH3GLB2
Entrez ID		9873	339965
HPRD ID		13321	13395
Ensembl ID		ENSG00000137478	ENSG00000163749
Uniprot IDs		O94868	Q5M9N0
PDB IDs		2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?
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