CDK11B and EIF3F

Number of citations of the paper that reports this interaction (PubMedID 19245811)
24

Data Source:
BioGRID (enzymatic study)

		CDK11B	EIF3F
Description		cyclin dependent kinase 11B	eukaryotic translation initiation factor 3 subunit F
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Translation Initiation Factor Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Translation Initiation Factor Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Regulation Of Gene Expression Regulation Of MRNA Processing	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Protein Deubiquitination IRES-dependent Viral Translational Initiation
Pathways		Recruitment of mitotic centrosome proteins and complexes	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs			Quercetin
Diseases
GWAS		Body mass index ( 26426971)	Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depression (quantitative trait) ( 20800221)
Interacting Genes		24 interacting genes: AP2M1 CASP1 CASP3 CASP8 CCND3 CCNL2 CHEK2 EIF3F KAT7 MSN PAK1 PIN1 PPIL3 RANBP9 RPS27A TCEA2 TH TPPP URM1 YWHAB YWHAE YWHAG YWHAQ YWHAZ	19 interacting genes: APP ATXN1 CDK11A CDK11B CDK19 DKC1 EEF1A1 EIF3M FBXO32 HAX1 HNRNPK HTR2A MCPH1 MSH4 MTOR PTN RPS6KB1 SHBG SMAD9
Entrez ID		984	8665
HPRD ID		08909	04887
Ensembl ID		ENSG00000248333	ENSG00000175390
Uniprot IDs		B4DII1 P21127	O00303
PDB IDs			3J8B 3J8C
Enriched GO Terms of Interacting Partners?
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