CDA and PLEKHB2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CDA	PLEKHB2
Description		cytidine deaminase	pleckstrin homology domain containing B2
Image
GO Annotations	Cellular Component	Extracellular Region Cytosol Secretory Granule Lumen Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Integral Component Of Membrane Recycling Endosome Membrane
	Molecular Function	Nucleoside Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Pyrimidine-containing Compound Salvage Cytidine Deamination Cytosine Metabolic Process Negative Regulation Of Cell Growth Pyrimidine Nucleoside Salvage Neutrophil Degranulation Negative Regulation Of Nucleotide Metabolic Process	Regulation Of Cell Differentiation
Pathways		Neutrophil degranulation Pyrimidine salvage
Drugs		1-Beta-Ribofuranosyl-1,3-Diazepinone
Diseases
GWAS		Mean corpuscular volume ( 27863252) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		10 interacting genes: FNDC11 KPNA2 LNX1 NTAQ1 PLEKHB2 PSMA1 PTGER3 SDCBP ZBTB24 ZNF598	9 interacting genes: ATF7IP BHLHE40 C1orf94 CDA DAZAP2 EPN1 MAP3K1 STAM2 UPF1
Entrez ID		978	55041
HPRD ID		11744	15144
Ensembl ID		ENSG00000158825	ENSG00000115762
Uniprot IDs		P32320	A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7
PDB IDs		1MQ0	3AJ4 3VIA
Enriched GO Terms of Interacting Partners?
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