RIMS2 and RAPGEF4

  • Number of citations of the paper that reports this interaction (PubMedID 11598134)
  • 106
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

RIMS2

RAPGEF4

Description regulating synaptic membrane exocytosis 2 Rap guanine nucleotide exchange factor 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cocaine dependence ( 23958962)
  • High density lipoprotein cholesterol levels ( 30498476)
  • Monoclonal gammopathy of undetermined significance ( 30737484)
  • Multiple system atrophy (pathologically confirmed) ( 27629089)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Fasting plasma glucose ( 25187374)
  • GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273)
  • Hippocampal volume ( 25625606)
  • Lateral ventricle temporal horn volume ( 31530798)
Interacting Genes 13 interacting genes: ABCA1 CACNA1S PABPC1 RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH 12 interacting genes: ATXN1 BMERB1 LRRK2 MAP1A RAP1A RAP2A RIMS2 RRAS2 SWAP70 TRAF2 TSPOAP1 ZC3H11A
Entrez ID 9699 11069
HPRD ID 09436 06929
Ensembl ID ENSG00000176406 ENSG00000091428
Uniprot IDs Q9UQ26 B7Z278 Q8WZA2 X5D7N4
PDB IDs 1V27 1WFG
Enriched GO Terms of Interacting Partners?
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