EIF5B and EIF1AX

Number of citations of the paper that reports this interaction (PubMedID 12514125)
62

		EIF5B	EIF1AX
Description		eukaryotic translation initiation factor 5B	eukaryotic translation initiation factor 1A X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytosol
	Molecular Function	RNA Binding Translation Initiation Factor Activity GTPase Activity Protein Binding GTP Binding Metal Ion Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding
	Biological Process	Translational Initiation Regulation Of Translational Initiation	Translational Initiation
Pathways		GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Interacting Genes		10 interacting genes: BRCA1 CBL CSNK2A1 ECT2 EIF1AX ETS1 PAXIP1 SIRPA TFCP2 ZBTB3	8 interacting genes: APP EIF2S1 EIF3C EIF5 EIF5B HSPB1 IKBKG IPO13
Entrez ID		9669	1964
HPRD ID		07304	02174
Ensembl ID		ENSG00000158417	ENSG00000173674
Uniprot IDs		O60841 Q8N5A0	P47813
PDB IDs			1D7Q 3ZJY 4KZY 4KZZ
Enriched GO Terms of Interacting Partners?
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