FEZ2 and SMC3

Number of citations of the paper that reports this interaction (PubMedID 16484223)
20

Data Source:
BioGRID (two hybrid)

		FEZ2	SMC3
Description		fasciculation and elongation protein zeta 2	structural maintenance of chromosomes 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Axon	Chromosome, Centromeric Region Chromatin Lateral Element Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Meiotic Cohesin Complex Nuclear Meiotic Cohesin Complex Mitotic Spindle Pole
	Molecular Function	Protein Binding	Chromatin Binding Microtubule Motor Activity Protein Binding ATP Binding Mediator Complex Binding Protein Heterodimerization Activity Beta-tubulin Binding Dynein Complex Binding
	Biological Process	Signal Transduction Nervous System Development Axon Guidance Negative Regulation Of Autophagosome Assembly	Mitotic Cell Cycle Regulation Of DNA Replication DNA Repair Sister Chromatid Cohesion Stem Cell Population Maintenance Cell Division Meiotic Cell Cycle Regulation Of Mitotic Spindle Assembly
Pathways			Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases			Cornelia de Lange syndrome (CdLS)
GWAS		Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Offspring birth weight ( 31043758)	Lumbar spine bone mineral density (integral) ( 27476799) Metabolite levels ( 23823483)
Interacting Genes		17 interacting genes: BRD1 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SMC3 TBC1D25 TEDC2 TLK2 WWC1 ZNF251	17 interacting genes: APC CEP63 DISC1 ESCO2 ESR1 FEZ1 FEZ2 KIFAP3 MTNR1B MXD1 MXD3 MXD4 MXI1 RPGR SMC1A SMC1B TRAF3IP1
Entrez ID		9637	9126
HPRD ID		09213	05829
Ensembl ID		ENSG00000171055	ENSG00000108055
Uniprot IDs		Q9UHY8	Q9UQE7
PDB IDs
Enriched GO Terms of Interacting Partners?
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