AATK and CDC25B

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		AATK	CDC25B
Description		apoptosis associated tyrosine kinase	cell division cycle 25B
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding
	Biological Process	Biological_process Peptidyl-tyrosine Phosphorylation	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Oocyte Maturation Protein Phosphorylation Female Meiosis I Positive Regulation Of Cell Proliferation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Mitotic Cell Cycle Cell Division Positive Regulation Of G2/MI Transition Of Meiotic Cell Cycle
Pathways			Cyclin A/B1/B2 associated events during G2/M transition Cyclin A:Cdk2-associated events at S phase entry Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs			Cysteinesulfonic Acid
Diseases
GWAS		Neuroticism ( 29255261) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Basophil percentage of granulocytes ( 27863252) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		40 interacting genes: CDC14A CDC25B CDK5 DUPD1 DUSP1 DUSP14 DUSP5 DUSP6 DUSP9 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TPTE2	27 interacting genes: AATK AR AURKA BRSK1 BRSK2 CDC14A CDK1 CDK2 CDK5 CHEK1 CREBBP CSNK2A1 CSNK2B ESR1 FHL3 KAT2B MAPK14 MAPK9 MAPKAPK2 MELK PGR SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ
Entrez ID		9625	994
HPRD ID		05591	00307
Ensembl ID		ENSG00000181409	ENSG00000101224
Uniprot IDs		H7C175 Q6ZMQ8	B3KS38 B4DIG0 B4DQZ3 B4DRC3 E1YMX4 G8JLH2 P30305 Q6MZW8
PDB IDs			1CWR 1CWS 1CWT 1QB0 1YM9 1YMD 1YMK 1YML 1YS0 2A2K 2IFD 2IFV 2UZQ 3FQT 3FQU 4WH7 4WH9
Enriched GO Terms of Interacting Partners?
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